About RWD domain-containing protein 3
RWD domain-containing protein 3 (RWDD3) is a protein
from Homo sapiens identified by UniProt accession
Q9Y3V2, 267 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | RWD domain-containing protein 3 |
| UniProt accession | Q9Y3V2 |
| Gene | RWDD3 |
| Organism | Homo sapiens |
| Length | 267 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- body mass index · score 0.33
- self reported educational attainment · score 0.28
- intelligence · score 0.28
- platelet component distribution width · score 0.27
- myeloid white cell count · score 0.26
- cognitive function measurement · score 0.26
- gut microbiome measurement · score 0.25
- lifestyle measurement · score 0.21
- neutrophil count · score 0.21
- motion sickness · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9Y3V2-F1 | alphafold | PREDICTED | 81.65 | — |
Amino-acid sequence (267 residues)
MAEPVQEELS VLAAIFCRPH EWEVLSRSET DGTVFRIHTK AEGFMDVDIP LELVFHLPVN YPSCLPGISI NSEQLTRAQC VTVKENLLEQ AESLLSEPMV HELVLWIQQN LRHILSQPET GSGSEKCTFS TSTTMDDGLW ITLLHLDHMR AKTKYVKIVE KWASDLRLTG RLMFMGKIIL ILLQGDRNNL KEYLILQKTS KVDVDSSGKK CKEKMISVLF ETKVQTEHKR FLAFEVKEYS ALDELQKEFE TAGLKKLFSE FVLALVK
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