Cysteine sulfinic acid decarboxylase (CSAD)

About Cysteine sulfinic acid decarboxylase

Cysteine sulfinic acid decarboxylase (CSAD) is a protein from Homo sapiens identified by UniProt accession Q9Y600, 493 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.

Target properties

Protein name	Cysteine sulfinic acid decarboxylase
UniProt accession	Q9Y600
Gene	CSAD
Organism	Homo sapiens
Length	493 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (65)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
Alzheimer disease · score 0.28
lysosomal storage disease · score 0.28
Parkinson disease · score 0.28
multiple sclerosis · score 0.28
mathematical ability · score 0.18
lymphocyte count · score 0.16
type 1 diabetes mellitus · score 0.16
self reported educational attainment · score 0.15
non-alcoholic fatty liver disease · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y600-F1	alphafold	PREDICTED	96.51	—

Amino-acid sequence (493 residues)

MADSEALPSL AGDPVAVEAL LRAVFGVVVD EAIQKGTSVS QKVCEWKEPE ELKQLLDLEL RSQGESQKQI LERCRAVIRY SVKTGHPRFF NQLFSGLDPH ALAGRIITES LNTSQYTYEI APVFVLMEEE VLRKLRALVG WSSGDGIFCP GGSISNMYAV NLARYQRYPD CKQRGLRTLP PLALFTSKEC HYSIQKGAAF LGLGTDSVRV VKADERGKMV PEDLERQIGM AEAEGAVPFL VSATSGTTVL GAFDPLEAIA DVCQRHGLWL HVDAAWGGSV LLSQTHRHLL DGIQRADSVA WNPHKLLAAG LQCSALLLQD TSNLLKRCHG SQASYLFQQD KFYDVALDTG DKVVQCGRRV DCLKLWLMWK AQGDQGLERR IDQAFVLARY LVEEMKKREG FELVMEPEFV NVCFWFVPPS LRGKQESPDY HERLSKVAPV LKERMVKEGS MMIGYQPHGT RGNFFRVVVA NSALTCADMD FLLNELERLG QDL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards