Amorolfine

DERMATOLOGICALS

Key facts

Amorolfine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including SCN9A.

• Molecular targets: SCN9A (1 listed in DrugCentral).
• ATC code: D01AE16 (Other antifungals for topical use).
• Molecular formula: C21H35NO; molecular weight 317.52 g/mol.

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Sodium channel protein type 9 subunit alpha	SCN9A	blocker	IC50 5.18

ATC classification

ATC code	Therapeutic hierarchy
D01AE16	DERMATOLOGICALS › ANTIFUNGALS FOR DERMATOLOGICAL USE › ANTIFUNGALS FOR TOPICAL USE › Other antifungals for topical use

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Pseudoaldosteronism	68.5
Craniofacial deformity	59.2
Coloboma	59.2
Epiphyses premature fusion	54.2
Pulmonary malformation	53.3
Pathogen resistance	52.9
Cystic eyeball, congenital	49.8
Congenital hand malformation	49.6

Chemical structure

• Molecular formula: C₂₁H₃₅NO
• Molecular weight: 317.52 g/mol
• CAS number: 78613-35-1
• InChIKey: MQHLMHIZUIDKOO-AYHJJNSGSA-N
• PubChem CID: 54260

CCC(C)(C)C1=CC=C(CC(C)CN2C[C@H](C)O[C@H](C)C2)C=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Amorolfine work?

Its molecular targets in DrugCentral include SCN9A (blocker).

What is the chemical formula of Amorolfine?

Amorolfine has the molecular formula C21H35NO and a molecular weight of 317.52 g/mol.

Sources

• DrugCentral drug card 188 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL489411 — compound record and bioactivity
• PubChem CID 54260 — chemical identifiers
• DrugBank DB09056 — drug record
• FDA UNII AB0BHP2FH0 — substance identity
• UniProt Q15858 (SCN9A) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.