Carperitide
Drug profile
Also known as: atriopeptin, carperitide (recombinant), human atrial natriuretic peptide
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Carperitide is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including NPR1 and Npr1.
- Molecular targets: NPR1 and Npr1 (2 listed in DrugCentral).
- Molecular formula: C127H203N45O39S3; molecular weight 3080.50 g/mol.
Mechanism & targets
Molecular targets (2)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Atrial natriuretic peptide receptor 1 | NPR1 | unknown | EC50 10.00 |
| Atrial natriuretic peptide receptor 1 | Npr1 | unknown | EC50 9.00 |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Cardiac failure | 123.4 |
| Renal impairment | 82.2 |
| Hypernatraemia | 68.4 |
| Cardiac failure chronic | 68.2 |
| Hepatic function abnormal | 60.7 |
| Cardiac failure acute | 46.5 |
| Blood pressure decreased | 44.5 |
| Blood urea increased | 43.9 |
| Disseminated intravascular coagulation | 41.6 |
| Cerebral infarction | 38.0 |
Chemical structure
| Molecular formula | C127H203N45O39S3 |
|---|---|
| Molecular weight | 3080.50 g/mol |
| CAS number | — |
| InChIKey | NSQLIUXCMFBZME-MPVJKSABSA-N |
| PubChem CID | 16129708 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Carperitide work?
Its molecular targets in DrugCentral include NPR1 and Npr1.
What is the chemical formula of Carperitide?
Carperitide has the molecular formula C127H203N45O39S3 and a molecular weight of 3080.50 g/mol.
Browse: all drugs starting with C · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 515 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2104386 — compound record and bioactivity
- PubChem CID 16129708 — chemical identifiers
- DrugBank DB15591 — drug record
- FDA UNII GZ8FA500J0 — substance identity
- UniProt P16066 (NPR1) — target protein
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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