Cedazuridine

Drug profile

Key facts

Cedazuridine is an onp drug catalogued in DrugCentral. It was first approved by the FDA in 2020. DrugCentral lists 1 molecular target, including CDA. Recorded indications include Chronic myelomonocytic leukemia and Myelodysplastic syndrome.

• Approval status: onp (first approved 2020 by the FDA).
• Molecular targets: CDA (1 listed in DrugCentral).
• Indications: Chronic myelomonocytic leukemia and Myelodysplastic syndrome.
• Molecular formula: C9H14F2N2O5; molecular weight 268.22 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Chronic myelomonocytic leukemia
• Myelodysplastic syndrome

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Cytidine deaminase	CDA	inhibitor	IC50 6.39

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2020-07-07	FDA	—	OTSUKA	Yes

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Cedazuridine is on its molecule page.

• Molecular formula: C₉H₁₄F₂N₂O₅
• Molecular weight: 268.22 g/mol
• CAS number: —
• InChIKey: VUDZSIYXZUYWSC-DBRKOABJSA-N
• PubChem CID: 25267009

C1CN(C(=O)N[C@@H]1O)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cedazuridine used for?

DrugCentral lists the following indications for Cedazuridine: Chronic myelomonocytic leukemia and Myelodysplastic syndrome.

How does Cedazuridine work?

Its molecular targets in DrugCentral include CDA (inhibitor).

When was Cedazuridine first approved?

Cedazuridine was first approved by the FDA in 2020.

What is the chemical formula of Cedazuridine?

Cedazuridine has the molecular formula C9H14F2N2O5 and a molecular weight of 268.22 g/mol.

Sources

• DrugCentral drug card 5402 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL3237547 — compound record and bioactivity
• PubChem CID 25267009 — chemical identifiers
• DrugBank DB15694 — drug record
• FDA UNII 39IS23Q1EW — substance identity
• DailyMed: FDA labels for Cedazuridine — current prescribing information (label search)
• UniProt P32320 (CDA) — target protein

How this page is built: methodology · editorial policy & corrections.