Ceftolozane

Cephalosporin Antibacterial — ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Ceftolozane is an onp drug in the Cephalosporin Antibacterial class catalogued in DrugCentral. It was first approved by the FDA in 2014. Recorded indications include Abdominal abscess, Abscess of liver, Acute pyelonephritis and Bacterial cystitis.

• Approval status: onp (first approved 2014 by the FDA).
• Drug class: Cephalosporin Antibacterial.
• Indications: Abdominal abscess, Abscess of liver, Acute pyelonephritis, Bacterial cystitis and Bacterial peritonitis and others.
• ATC code: J01DI54 (Other cephalosporins and penems).
• Molecular formula: C23H31N12O8S2+; molecular weight 667.71 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (14)

• Abdominal abscess
• Abscess of liver
• Acute pyelonephritis
• Bacterial cystitis
• Bacterial peritonitis
• Bacterial pyelonephritis
• Cholecystitis
• Haemophilus influenzae pneumonia
• Infectious disease of abdomen
• Nosocomial pneumonia
• Sepsis caused by Haemophilus influenzae
• Sepsis caused by Serratia
• Urinary tract infectious disease
• Ventilator-acquired pneumonia

Mechanism & targets

• Established pharmacologic class: Cephalosporin Antibacterial

Regulatory approvals (3)

Date	Agency	Marketed as	Applicant	Orphan
2019-01-08	PMDA	—	MSD K.K.
2015-09-18	EMA	—	MERCK SHARP & DOHME B.V.
2014-12-19	FDA	—	CUBIST PHARMS

ATC classification

ATC code	Therapeutic hierarchy
J01DI54	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › OTHER BETA-LACTAM ANTIBACTERIALS › Other cephalosporins and penems

Chemical structure

• Molecular formula: C₂₃H₃₁N₁₂O₈S₂+
• Molecular weight: 667.71 g/mol
• CAS number: —
• InChIKey: JHFNIHVVXRKLEF-DCZLAGFPSA-O
• PubChem CID: 53234134

CN1C(N)=C(NC(=O)NCCN)C=[N+]1CC1=C(N2[C@H](SC1)[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=NSC(N)=N1)C2=O)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Ceftolozane used for?

DrugCentral lists the following indications for Ceftolozane: Abdominal abscess, Abscess of liver, Acute pyelonephritis, Bacterial cystitis, Bacterial peritonitis, Bacterial pyelonephritis, Cholecystitis and Haemophilus influenzae pneumonia and others.

When was Ceftolozane first approved?

Ceftolozane was first approved by the FDA in 2014.

What drug class does Ceftolozane belong to?

Ceftolozane is in the Cephalosporin Antibacterial class.

What is the chemical formula of Ceftolozane?

Ceftolozane has the molecular formula C23H31N12O8S2+ and a molecular weight of 667.71 g/mol.

Sources

• DrugCentral drug card 4922 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1213250 — compound record and bioactivity
• PubChem CID 53234134 — chemical identifiers
• DrugBank DB09050 — drug record
• FDA UNII 37A4IES95Q — substance identity
• DailyMed: FDA labels for Ceftolozane — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.