Cyclacillin

Drug profile

Key facts

Cyclacillin is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1979. DrugCentral lists 2 molecular targets, including pbpA and mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB. Recorded indications include Bronchitis, Infection of skin AND/OR subcutaneous tissue, Infective otitis media and Pharyngitis.

• Approval status: ofm (first approved 1979 by the FDA).
• Molecular targets: pbpA and mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB (2 listed in DrugCentral).
• Indications: Bronchitis, Infection of skin AND/OR subcutaneous tissue, Infective otitis media, Pharyngitis and Urinary tract infectious disease.
• Molecular formula: C15H23N3O4S; molecular weight 341.43 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (5)

• Bronchitis
• Infection of skin AND/OR subcutaneous tissue
• Infective otitis media
• Pharyngitis
• Urinary tract infectious disease

Off-label uses (2)

• Cholangitis
• Sinusitis

Contraindications (3)

• Infectious mononucleosis
• Kidney disease
• Pseudomembranous enterocolitis

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Penicillin-binding protein 1A	pbpA	unknown	—
Bacterial penicillin-binding protein	mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1979-09-13	FDA	—	WYETH AYERST

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Cyclacillin is on its molecule page.

• Molecular formula: C₁₅H₂₃N₃O₄S
• Molecular weight: 341.43 g/mol
• CAS number: —
• InChIKey: HGBLNBBNRORJKI-WCABBAIRSA-N
• PubChem CID: 19003

CC1(C)S[C@@H]2[C@H](NC(=O)C3(N)CCCCC3)C(=O)N2[C@H]1C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cyclacillin used for?

DrugCentral lists the following indications for Cyclacillin: Bronchitis, Infection of skin AND/OR subcutaneous tissue, Infective otitis media, Pharyngitis and Urinary tract infectious disease.

How does Cyclacillin work?

Its molecular targets in DrugCentral include pbpA and mrcA|mrcB|dacC|mrdA|ftsI|dacA|dacB (inhibitor).

When was Cyclacillin first approved?

Cyclacillin was first approved by the FDA in 1979.

What is the chemical formula of Cyclacillin?

Cyclacillin has the molecular formula C15H23N3O4S and a molecular weight of 341.43 g/mol.

Sources

• DrugCentral drug card 632 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200356 — compound record and bioactivity
• PubChem CID 19003 — chemical identifiers
• DrugBank DB01000 — drug record
• FDA UNII 72ZJ154X86 — substance identity
• DailyMed: FDA labels for Cyclacillin — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.