Docusate sodium

ALIMENTARY TRACT AND METABOLISM

Key facts

Docusate sodium is a drug catalogued in DrugCentral. Recorded indications include Breastfeeding (mother), Constipation, Iron deficiency anemia and Megaloblastic anemia due to folate deficiency.

• Indications: Breastfeeding (mother), Constipation, Iron deficiency anemia, Megaloblastic anemia due to folate deficiency and Pregnancy, function.
• ATC code: A06AA02 (Softeners, emollients).
• Molecular formula: C20H38O7S; molecular weight 422.58 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (5)

• Breastfeeding (mother)
• Constipation
• Iron deficiency anemia
• Megaloblastic anemia due to folate deficiency
• Pregnancy, function

Off-label uses (2)

• Incomplete passage of stool
• Prevention of Fetal Neural Tube Defects during Pregnancy

Contraindications (21)

• Anemia due to enzyme deficiency
• Appendicitis
• Atrophic gastritis
• Bleeding hemorrhoids
• Disorder of mucous membrane
• Diverticular disease
• Gastrectomy
• Gastroenteritis
• Gastrointestinal obstruction
• Hb SS disease
• Hemochromatosis
• Hemolytic anemia
• Hemosiderosis
• Hypokalemia
• Incontinence of feces
• Leber's optic atrophy
• Peptic ulcer
• Primary hyperoxaluria
• Repeated Blood Transfusions
• Ulcerative colitis
• Urinary incontinence

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
A06AA02	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR CONSTIPATION › DRUGS FOR CONSTIPATION › Softeners, emollients
A06AG10	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR CONSTIPATION › DRUGS FOR CONSTIPATION › Enemas

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Constipation	881.8
Drug ineffective	574.5
Systemic lupus erythematosus	531.9
Pemphigus	519.8
Hand deformity	487.6
Synovitis	419.1
Glossodynia	391.4
Duodenal ulcer perforation	363.9
Helicobacter infection	314.2
Folliculitis	306.3
Pericarditis	292.2
Maternal exposure during pregnancy	289.5

Chemical structure

• Molecular formula: C₂₀H₃₈O₇S
• Molecular weight: 422.58 g/mol
• CAS number: 10041-19-7
• InChIKey: HNSDLXPSAYFUHK-UHFFFAOYSA-N
• PubChem CID: 23673837

CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(O)(=O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Docusate sodium used for?

DrugCentral lists the following indications for Docusate sodium: Breastfeeding (mother), Constipation, Iron deficiency anemia, Megaloblastic anemia due to folate deficiency and Pregnancy, function.

What is the chemical formula of Docusate sodium?

Docusate sodium has the molecular formula C20H38O7S and a molecular weight of 422.58 g/mol.

Sources

• DrugCentral drug card 941 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1477036 — compound record and bioactivity
• PubChem CID 23673837 — chemical identifiers
• DrugBank DB11089 — drug record
• FDA UNII F05Q2T2JA0 — substance identity
• DailyMed: FDA labels for Docusate sodium — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.