Methylphenobarbital

NERVOUS SYSTEM

Key facts

Methylphenobarbital is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1935. DrugCentral lists 1 molecular target, including GABRA1|GABRG2|GABRB3. Recorded indications include Anxiety, Apprehension, Epilepsy and Tension.

• Molecular targets: GABRA1|GABRG2|GABRB3 (1 listed in DrugCentral).
• Indications: Anxiety, Apprehension, Epilepsy, Tension and Tonic-clonic epilepsy.
• ATC code: N03AA01 (Barbiturates and derivatives).
• Molecular formula: C13H14N2O3; molecular weight 246.27 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (5)

• Anxiety
• Apprehension
• Epilepsy
• Tension
• Tonic-clonic epilepsy

Contraindications (21)

• Acute exacerbation of asthma
• Alcoholism
• Anemia
• Chronic obstructive lung disease
• Depressive disorder
• Disease of liver
• Hepatic coma
• Hepatic encephalopathy
• Hepatic failure
• Hyperactive behavior
• Hyperammonemia
• Kidney disease
• Neutropenic disorder
• Porphyria
• Pregnancy, function
• Respiratory insufficiency
• Sleep apnea
• Sleep automatism
• Substance abuse
• Suicidal thoughts
• Thrombocytopenic disorder

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
GABA-A receptor alpha-1/beta-3/gamma-2	GABRA1|GABRG2|GABRB3	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1935-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
N03AA01	NERVOUS SYSTEM › ANTIEPILEPTICS › ANTIEPILEPTICS › Barbiturates and derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Methylphenobarbital is on its molecule page.

• Molecular formula: C₁₃H₁₄N₂O₃
• Molecular weight: 246.27 g/mol
• CAS number: 115-38-8
• InChIKey: ALARQZQTBTVLJV-UHFFFAOYSA-N
• PubChem CID: 8271

CCC1(C(=O)NC(=O)N(C)C1=O)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Methylphenobarbital used for?

DrugCentral lists the following indications for Methylphenobarbital: Anxiety, Apprehension, Epilepsy, Tension and Tonic-clonic epilepsy.

How does Methylphenobarbital work?

Its molecular targets in DrugCentral include GABRA1|GABRG2|GABRB3.

When was Methylphenobarbital first approved?

Methylphenobarbital was first approved by the YEAR INTRODUCED in 1935.

What is the chemical formula of Methylphenobarbital?

Methylphenobarbital has the molecular formula C13H14N2O3 and a molecular weight of 246.27 g/mol.

Sources

• DrugCentral drug card 1696 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL45029 — compound record and bioactivity
• PubChem CID 8271 — chemical identifiers
• DrugBank DB00849 — drug record
• FDA UNII 5NC67NU76B — substance identity

How this page is built: methodology · editorial policy & corrections.