Progabide
NERVOUS SYSTEM
Also known as: gabren, gabrene, halogabide
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Progabide is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1985. DrugCentral lists 3 molecular targets, including Gabrp|Gabrb1|Gabrd|Gabrg2|Gabra5|Gabra3|Gabrg1|Gabra2|Gabra4|Gabrg3|Gabra6|Gabra1|Gabrb3|Gabrb2|Gabrq|Gabre, GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ and GABRA1|GABRG2|GABRB2.
- Molecular targets: Gabrp|Gabrb1|Gabrd|Gabrg2|Gabra5|Gabra3|Gabrg1|Gabra2|Gabra4|Gabrg3|Gabra6|Gabra1|Gabrb3|Gabrb2|Gabrq|Gabre, GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ and GABRA1|GABRG2|GABRB2 (3 listed in DrugCentral).
- ATC code: N03AG05 (Fatty acid derivatives).
- Molecular formula: C17H16ClFN2O2; molecular weight 334.78 g/mol.
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| GABA-A receptor; anion channel | Gabrp|Gabrb1|Gabrd|Gabrg2|Gabra5|Gabra3|Gabrg1|Gabra2|Gabra4|Gabrg3|Gabra6|Gabra1|Gabrb3|Gabrb2|Gabrq|Gabre | unknown | Ki 4.85 |
| GABA-A receptor; anion channel | GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ | unknown | Ki 4.40 |
| GABA-A receptor alpha-1/beta-2/gamma-2 | GABRA1|GABRG2|GABRB2 | unknown | Ki 4.40 |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1985-01-01 | YEAR INTRODUCED | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N03AG05 | NERVOUS SYSTEM › ANTIEPILEPTICS › ANTIEPILEPTICS › Fatty acid derivatives |
Chemical structure
| Molecular formula | C17H16ClFN2O2 |
|---|---|
| Molecular weight | 334.78 g/mol |
| CAS number | 62666-20-0 |
| InChIKey | IBALRBWGSVJPAP-UHFFFAOYSA-N |
| PubChem CID | 44115 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Progabide work?
Its molecular targets in DrugCentral include Gabrp|Gabrb1|Gabrd|Gabrg2|Gabra5|Gabra3|Gabrg1|Gabra2|Gabra4|Gabrg3|Gabra6|Gabra1|Gabrb3|Gabrb2|Gabrq|Gabre, GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ and GABRA1|GABRG2|GABRB2.
When was Progabide first approved?
Progabide was first approved by the YEAR INTRODUCED in 1985.
What is the chemical formula of Progabide?
Progabide has the molecular formula C17H16ClFN2O2 and a molecular weight of 334.78 g/mol.
Browse: all drugs starting with P · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 2278 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL287631 — compound record and bioactivity
- PubChem CID 44115 — chemical identifiers
- DrugBank DB00837 — drug record
- FDA UNII 38C836J57Z — substance identity
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