Pyrantel

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

Key facts

Pyrantel is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1974. DrugCentral lists 1 molecular target, including ACHE. Recorded indications include Ascariasis, Enterobiasis and Mixed intestinal infection due to Class Cestoda and/or Class Trematoda and/or Phylum Nemata.

• Molecular targets: ACHE (1 listed in DrugCentral).
• Indications: Ascariasis, Enterobiasis and Mixed intestinal infection due to Class Cestoda and/or Class Trematoda and/or Phylum Nemata.
• ATC code: P02CC01 (Tetrahydropyrimidine derivatives).
• Molecular formula: C11H14N2S; molecular weight 206.31 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (3)

• Ascariasis
• Enterobiasis
• Mixed intestinal infection due to Class Cestoda and/or Class Trematoda and/or Phylum Nemata

Off-label uses (5)

• Ancylostoma Duodenale Infection
• Infection by Moniliformis
• Infection by Uncinaria
• Necator Americanus Infection
• Trichostrongyliasis

Contraindications (1)

• Disease of liver

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Acetylcholinesterase	ACHE	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1974-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
P02CC01	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS › ANTHELMINTICS › ANTINEMATODAL AGENTS › Tetrahydropyrimidine derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Pyrantel is on its molecule page.

• Molecular formula: C₁₁H₁₄N₂S
• Molecular weight: 206.31 g/mol
• CAS number: 15686-83-6
• InChIKey: YSAUAVHXTIETRK-AATRIKPKSA-N
• PubChem CID: 708857

CN1CCCN=C1\C=C\C1=CC=CS1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Pyrantel used for?

DrugCentral lists the following indications for Pyrantel: Ascariasis, Enterobiasis and Mixed intestinal infection due to Class Cestoda and/or Class Trematoda and/or Phylum Nemata.

How does Pyrantel work?

Its molecular targets in DrugCentral include ACHE.

When was Pyrantel first approved?

Pyrantel was first approved by the YEAR INTRODUCED in 1974.

What is the chemical formula of Pyrantel?

Pyrantel has the molecular formula C11H14N2S and a molecular weight of 206.31 g/mol.

Sources

• DrugCentral drug card 2999 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1585303 — compound record and bioactivity
• PubChem CID 708857 — chemical identifiers
• DrugBank DB11156 — drug record
• FDA UNII 4QIH0N49E7 — substance identity

How this page is built: methodology · editorial policy & corrections.