Succimer

Lead Chelator

Key facts

Succimer is an ofp drug in the Lead Chelator class catalogued in DrugCentral. It was first approved by the FDA in 1991. Its mechanism of action is classified as Lead Chelating Activity. Recorded indications include Accidental poisoning by lead and its compounds and fumes.

• Approval status: ofp (first approved 1991 by the FDA).
• Drug class: Lead Chelator.
• Mechanism of action: Lead Chelating Activity.
• Indications: Accidental poisoning by lead and its compounds and fumes.
• Molecular formula: C4H6O4S2; molecular weight 182.22 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Accidental poisoning by lead and its compounds and fumes

Mechanism & targets

• Mechanism of action (MoA): Lead Chelating Activity
• Established pharmacologic class: Lead Chelator

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1991-01-30	FDA	—	RECORDATI RARE	Yes

Pharmacogenomics

Drug-label and guideline annotations from PharmGKB and CPIC.

• FDA label: G6PD

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Succimer is on its molecule page.

• Molecular formula: C₄H₆O₄S₂
• Molecular weight: 182.22 g/mol
• CAS number: —
• InChIKey: ACTRVOBWPAIOHC-XIXRPRMCSA-N
• PubChem CID: 2724354

OC(=O)[C@@H](S)[C@@H](S)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Succimer used for?

DrugCentral lists the following indications for Succimer: Accidental poisoning by lead and its compounds and fumes.

How does Succimer work?

Succimer is classified as Lead Chelating Activity.

When was Succimer first approved?

Succimer was first approved by the FDA in 1991.

What drug class does Succimer belong to?

Succimer is in the Lead Chelator class.

What is the chemical formula of Succimer?

Succimer has the molecular formula C4H6O4S2 and a molecular weight of 182.22 g/mol.

Sources

• DrugCentral drug card 2486 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1201073 — compound record and bioactivity
• PubChem CID 2724354 — chemical identifiers
• DrugBank DB00566 — drug record
• FDA UNII DX1U2629QE — substance identity
• DailyMed: FDA labels for Succimer — current prescribing information (label search)
• PharmGKB / CPIC — pharmacogenomic label annotations

How this page is built: methodology · editorial policy & corrections.