Sulopenem etzadroxil

Drug profile

Key facts

Sulopenem etzadroxil is an onp drug catalogued in DrugCentral. It was first approved by the FDA in 2024. DrugCentral lists 5 molecular targets, including ftsI, dacB and mrcA. Recorded indications include Urinary tract infections.

• Approval status: onp (first approved 2024 by the FDA).
• Molecular targets: ftsI, dacB, mrcA and mrcB (5 listed in DrugCentral).
• Indications: Urinary tract infections.
• Molecular formula: C19H27NO7S3; molecular weight 477.63 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Urinary tract infections

Mechanism & targets

Molecular targets (5)

Target	Gene	Action	Activity
Peptidoglycan synthase FtsI	ftsI	inhibitor	—
D-alanyl-D-alanine carboxypeptidase DacB	dacB	inhibitor	—
Penicillin-binding protein 1A	mrcA	inhibitor	—
Penicillin-binding protein 1B	mrcB	inhibitor	—
Penicillin-binding protein 2	mrdA	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2024-10-25	FDA	—	Iterum Therapeutics

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sulopenem etzadroxil is on its molecule page.

• Molecular formula: C₁₉H₂₇NO₇S₃
• Molecular weight: 477.63 g/mol
• CAS number: —
• InChIKey: NBPVNGWRLGHULH-CSOWVJSESA-N
• PubChem CID: 23642298

CCC(CC)C(=O)OCOC(=O)C1=C(S[C@H]2N1C(=O)[C@@H]2[C@@H](C)O)S[C@H]3CC[S@@](=O)C3

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Sulopenem etzadroxil used for?

DrugCentral lists the following indications for Sulopenem etzadroxil: Urinary tract infections.

How does Sulopenem etzadroxil work?

Its molecular targets in DrugCentral include ftsI (inhibitor), dacB (inhibitor), mrcA (inhibitor) and mrcB (inhibitor).

When was Sulopenem etzadroxil first approved?

Sulopenem etzadroxil was first approved by the FDA in 2024.

What is the chemical formula of Sulopenem etzadroxil?

Sulopenem etzadroxil has the molecular formula C19H27NO7S3 and a molecular weight of 477.63 g/mol.

Sources

• DrugCentral drug card 5838 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL4594246 — compound record and bioactivity
• PubChem CID 23642298 — chemical identifiers
• DrugBank DB16335 — drug record
• FDA UNII 492M3I304T — substance identity
• DailyMed: FDA labels for Sulopenem etzadroxil — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.