Thiamylal
Drug profile
Also known as: thiamylal sodium, thioquinalbarbitone, thioseconal
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Thiamylal is an ofm drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ. Recorded indications include General anesthesia.
- Approval status: ofm.
- Molecular targets: GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ (1 listed in DrugCentral).
- Indications: General anesthesia.
- Molecular formula: C12H18N2O2S; molecular weight 254.35 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- General anesthesia
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| GABA-A receptor; anion channel | GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ | positive allosteric modulator | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| — | FDA | — | PARKEDALE |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Thiamylal is on its molecule page.
| Molecular formula | C12H18N2O2S |
|---|---|
| Molecular weight | 254.35 g/mol |
| CAS number | 77-27-0 |
| InChIKey | XLOMZPUITCYLMJ-UHFFFAOYSA-N |
| PubChem CID | 3032285 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Thiamylal used for?
DrugCentral lists the following indications for Thiamylal: General anesthesia.
How does Thiamylal work?
Its molecular targets in DrugCentral include GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ (positive allosteric modulator).
What is the chemical formula of Thiamylal?
Thiamylal has the molecular formula C12H18N2O2S and a molecular weight of 254.35 g/mol.
Browse: all drugs starting with T · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 2626 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1201065 — compound record and bioactivity
- PubChem CID 3032285 — chemical identifiers
- DrugBank DB01154 — drug record
- FDA UNII 01T23W89FR — substance identity
- DailyMed: FDA labels for Thiamylal — current prescribing information (label search)
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