Treosulfan

ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Key facts

Treosulfan is an onp drug catalogued in DrugCentral. It was first approved by the EMA in 2019. Recorded indications include Allogeneic peripheral blood stem cell transplant.

• Approval status: onp (first approved 2019 by the EMA).
• Indications: Allogeneic peripheral blood stem cell transplant.
• ATC code: L01AB02 (Alkyl sulfonates).
• Molecular formula: C6H14O8S2; molecular weight 278.29 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Allogeneic peripheral blood stem cell transplant

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2019-06-20	EMA	—	medac Gesellschaft fur klinische Spezialpraparate mbH	Yes

ATC classification

ATC code	Therapeutic hierarchy
L01AB02	ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS › ANTINEOPLASTIC AGENTS › ALKYLATING AGENTS › Alkyl sulfonates

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Cytomegalovirus infection reactivation	990.2
Adenovirus infection	886.0
Acute graft versus host disease in skin	842.0
Cytomegalovirus infection	743.8
Graft versus host disease in skin	609.6
Mucosal inflammation	534.1
Human herpesvirus 6 infection	506.7
Graft versus host disease in gastrointestinal tract	493.2
Acute graft versus host disease	419.1
Off label use	398.2
Acute graft versus host disease in intestine	328.2
Adenovirus reactivation	303.1

Chemical structure

• Molecular formula: C₆H₁₄O₈S₂
• Molecular weight: 278.29 g/mol
• CAS number: 299-75-2
• InChIKey: YCPOZVAOBBQLRI-WDSKDSINSA-N
• PubChem CID: 9882105

CS(=O)(=O)OC[C@H](O)[C@@H](O)COS(C)(=O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Treosulfan used for?

DrugCentral lists the following indications for Treosulfan: Allogeneic peripheral blood stem cell transplant.

When was Treosulfan first approved?

Treosulfan was first approved by the EMA in 2019.

What is the chemical formula of Treosulfan?

Treosulfan has the molecular formula C6H14O8S2 and a molecular weight of 278.29 g/mol.

Sources

• DrugCentral drug card 2718 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL455186 — compound record and bioactivity
• PubChem CID 9882105 — chemical identifiers
• DrugBank DB11678 — drug record
• FDA UNII CO61ER3EPI — substance identity
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.