Udenafil
GENITO URINARY SYSTEM AND SEX HORMONES
Also known as: DA-8159, zydena
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Udenafil is a drug catalogued in DrugCentral. It was first approved by the Korean Food and Drug Administration (KFDA) in 2005. DrugCentral lists 2 molecular targets, including PDE5A and ABCB1. Recorded indications include Impotence.
- Molecular targets: PDE5A and ABCB1 (2 listed in DrugCentral).
- Indications: Impotence.
- ATC code: G04BE11 (Drugs used in erectile dysfunction).
- Molecular formula: C25H36N6O4S; molecular weight 516.66 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Impotence
Mechanism & targets
Molecular targets (2)
| Target | Gene | Action | Activity |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | PDE5A | inhibitor | IC50 8.08 |
| Multidrug resistance protein 1 | ABCB1 | unknown | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 2005-12-31 | Korean Food and Drug Administration (KFDA) | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
G04BE11 | GENITO URINARY SYSTEM AND SEX HORMONES › UROLOGICALS › UROLOGICALS › Drugs used in erectile dysfunction |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Udenafil is on its molecule page.
| Molecular formula | C25H36N6O4S |
|---|---|
| Molecular weight | 516.66 g/mol |
| CAS number | 268203-93-6 |
| InChIKey | IYFNEFQTYQPVOC-UHFFFAOYSA-N |
| PubChem CID | 135413547 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Udenafil used for?
DrugCentral lists the following indications for Udenafil: Impotence.
How does Udenafil work?
Its molecular targets in DrugCentral include PDE5A (inhibitor) and ABCB1.
When was Udenafil first approved?
Udenafil was first approved by the Korean Food and Drug Administration (KFDA) in 2005.
What is the chemical formula of Udenafil?
Udenafil has the molecular formula C25H36N6O4S and a molecular weight of 516.66 g/mol.
Browse: all drugs starting with U · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4141 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2103849 — compound record and bioactivity
- PubChem CID 135413547 — chemical identifiers
- DrugBank DB06267 — drug record
- FDA UNII L5IB4XLY36 — substance identity
- UniProt O76074 (PDE5A) — target protein
- UniProt P08183 (ABCB1) — target protein
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