Urokinase
Thrombolytic Agent — BLOOD AND BLOOD FORMING ORGANS
Also known as: abbokinase, kinlytic
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Urokinase is a drug in the Thrombolytic Agent class catalogued in DrugCentral. DrugCentral lists 1 molecular target, including PLG. Recorded indications include Pulmonary embolism.
- Drug class: Thrombolytic Agent.
- Molecular targets: PLG (1 listed in DrugCentral).
- Indications: Pulmonary embolism.
- ATC code: B01AD04 (Enzymes).
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Pulmonary embolism
Mechanism & targets
| Established pharmacologic class | Thrombolytic Agent |
|---|
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Plasminogen | PLG | activator | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| — | FDA | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
B01AD04 | BLOOD AND BLOOD FORMING ORGANS › ANTITHROMBOTIC AGENTS › ANTITHROMBOTIC AGENTS › Enzymes |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Peliosis hepatis | 58.9 |
Chemical structure
| Molecular formula | — |
|---|---|
| Molecular weight | — |
| CAS number | 9039-53-6 |
| InChIKey | — |
| PubChem CID | — |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Urokinase used for?
DrugCentral lists the following indications for Urokinase: Pulmonary embolism.
How does Urokinase work?
Its molecular targets in DrugCentral include PLG (activator).
What drug class does Urokinase belong to?
Urokinase is in the Thrombolytic Agent class.
Browse: all drugs starting with U · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 5109 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1201420 — compound record and bioactivity
- DrugBank DB00013 — drug record
- FDA UNII 83G67E21XI — substance identity
- DailyMed: FDA labels for Urokinase — current prescribing information (label search)
- UniProt P00747 (PLG) — target protein
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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