N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide

C8H8F2N2OS — CID 103515709

IUPACN-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide
SMILESO=C(Nc1nc(C2CC2)cs1)C(F)F
InChIInChI=1S/C8H8F2N2OS/c9-6(10)7(13)12-8-11-5(3-14-8)4-1-2-4/h3-4,6H,1-2H2,(H,11,12,13)
InChIKeyRHOSAFYATMUHCT-UHFFFAOYSA-N
MW218.23 g/mol
LogP2.22
Rot. Bonds3

About N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide

N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide (PubChem CID 103515709) has the molecular formula C8H8F2N2OS and a molecular weight of 218.23 g/mol. Its IUPAC name is N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide.

Molecular Properties

Compound NameN-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide
PubChem CID103515709
Molecular FormulaC8H8F2N2OS
Molecular Weight218.23 g/mol
Exact Mass218.03
IUPAC NameN-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide
SMILESO=C(Nc1nc(C2CC2)cs1)C(F)F
InChIInChI=1S/C8H8F2N2OS/c9-6(10)7(13)12-8-11-5(3-14-8)4-1-2-4/h3-4,6H,1-2H2,(H,11,12,13)
InChIKeyRHOSAFYATMUHCT-UHFFFAOYSA-N
XLogP2.22
TPSA41.99 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds3
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500218.23
LogP ≤ 52.22
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-dimethylpropanamide
CID 60741010
N-(4-tert-Butyl-1,3-thiazol-2-yl)acetamide
CID 588190
N-(4-methyl-1,3-thiazol-2-yl)cyclopropanecarboxamide
CID 2421541
N-(4-cyclohexylthiazol-2-yl)propionamide
CID 5141035
N-(4-tert-butyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
CID 824432
4-(2,2-Difluorocyclopropyl)-1,3-thiazol-2-amine
CID 165692054
N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,3,3,3-tetrafluoro-2-methoxypropanamide
CID 3890722
methyl N-(4-cyclopropyl-1,3-thiazol-2-yl)-3,3,3-trifluoro-2-(propanoylamino)alaninate
CID 4260667
2-cyclohexyl-N-(4-cyclopropyl-1,3-thiazol-2-yl)acetamide
CID 32863321
2-cyclopentyl-N-(4-cyclopropyl-1,3-thiazol-2-yl)acetamide
CID 40033373
N-(4-tert-butyl-1,3-thiazol-2-yl)-2-(trifluoromethylsulfanyl)propanamide
CID 42959444
3-methyl-N-[4-(trifluoromethyl)-1,3-thiazol-2-yl]butanamide
CID 45884392

Frequently Asked Questions

What is the IUPAC name of N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide?
The IUPAC name of N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide (CID 103515709) is N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide.
What is the SMILES notation for N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide?
The canonical SMILES for N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide is O=C(Nc1nc(C2CC2)cs1)C(F)F.
What is the InChIKey of N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide?
The InChIKey is RHOSAFYATMUHCT-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H8F2N2OS/c9-6(10)7(13)12-8-11-5(3-14-8)4-1-2-4/h3-4,6H,1-2H2,(H,11,12,13).
What are the key properties of N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide?
N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide has a molecular weight of 218.23 g/mol, XLogP of 2.22, 3 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide is sourced from PubChem (CID 103515709), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).