2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine

C10H9ClN4S — CID 107125320

IUPAC2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine
SMILESNc1cc(C2CC2)nc(-c2ncc(Cl)s2)n1
InChIInChI=1S/C10H9ClN4S/c11-7-4-13-10(16-7)9-14-6(5-1-2-5)3-8(12)15-9/h3-5H,1-2H2,(H2,12,14,15)
InChIKeyDOXOIMKDBAWXLY-UHFFFAOYSA-N
MW252.73 g/mol
LogP2.71
Rot. Bonds2

About 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine

2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine (PubChem CID 107125320) has the molecular formula C10H9ClN4S and a molecular weight of 252.73 g/mol. Its IUPAC name is 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine.

Molecular Properties

Compound Name2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine
PubChem CID107125320
Molecular FormulaC10H9ClN4S
Molecular Weight252.73 g/mol
Exact Mass252.02
IUPAC Name2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine
SMILESNc1cc(C2CC2)nc(-c2ncc(Cl)s2)n1
InChIInChI=1S/C10H9ClN4S/c11-7-4-13-10(16-7)9-14-6(5-1-2-5)3-8(12)15-9/h3-5H,1-2H2,(H2,12,14,15)
InChIKeyDOXOIMKDBAWXLY-UHFFFAOYSA-N
XLogP2.71
TPSA64.69 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms16
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500252.73
LogP ≤ 52.71
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Related Compounds

6-cyclopentyl-2-(1,3-thiazol-2-yl)pyrimidin-4-amine
CID 113390538
5-bromo-2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropyl-N-methylpyrimidin-4-amine
CID 107125379
6-cyclopropyl-2-thieno[3,2-b]pyridin-6-ylpyrimidin-4-amine
CID 81143436
6-cyclopropyl-2-(furan-2-yl)pyrimidin-4-amine
CID 63353570
5-bromo-2-(5-chloro-1,3-thiazol-2-yl)pyrimidin-4-amine
CID 107125371
6-cyclopropyl-2-quinolin-8-ylpyrimidin-4-amine
CID 63970784
2-(4-tert-butyl-6-chloropyrimidin-2-yl)-5-chloro-1,3-thiazole
CID 107124671
6-cyclopropyl-2-(2-ethylphenyl)pyrimidin-4-amine
CID 63354241
6-cyclopropyl-4-methylpyridin-2-amine
CID 45078995
6-cyclobutylpyrimidine-2,4-diamine
CID 156773674
6-cyclopropylpyrimidin-4-amine
CID 45080491
2-(5-chloro-1,3-thiazol-2-yl)-N-methyl-6-propylpyrimidin-4-amine
CID 107125280

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine?
The IUPAC name of 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine (CID 107125320) is 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine.
What is the SMILES notation for 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine?
The canonical SMILES for 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine is Nc1cc(C2CC2)nc(-c2ncc(Cl)s2)n1.
What is the InChIKey of 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine?
The InChIKey is DOXOIMKDBAWXLY-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H9ClN4S/c11-7-4-13-10(16-7)9-14-6(5-1-2-5)3-8(12)15-9/h3-5H,1-2H2,(H2,12,14,15).
What are the key properties of 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine?
2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine has a molecular weight of 252.73 g/mol, XLogP of 2.71, 2 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(5-chloro-1,3-thiazol-2-yl)-6-cyclopropylpyrimidin-4-amine is sourced from PubChem (CID 107125320), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).