N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide

C19H16F2N4O — CID 109291695

IUPACN-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide
SMILESCCc1ccc(Nc2cnc(C(=O)Nc3ccc(F)cc3F)cn2)cc1
InChIInChI=1S/C19H16F2N4O/c1-2-12-3-6-14(7-4-12)24-18-11-22-17(10-23-18)19(26)25-16-8-5-13(20)9-15(16)21/h3-11H,2H2,1H3,(H,23,24)(H,25,26)
InChIKeyLYXXGRFOQSEEHZ-UHFFFAOYSA-N
MW354.36 g/mol
LogP4.31
Rot. Bonds5

About N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide

N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide (PubChem CID 109291695) has the molecular formula C19H16F2N4O and a molecular weight of 354.36 g/mol. Its IUPAC name is N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide
PubChem CID109291695
Molecular FormulaC19H16F2N4O
Molecular Weight354.36 g/mol
Exact Mass354.13
IUPAC NameN-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide
SMILESCCc1ccc(Nc2cnc(C(=O)Nc3ccc(F)cc3F)cn2)cc1
InChIInChI=1S/C19H16F2N4O/c1-2-12-3-6-14(7-4-12)24-18-11-22-17(10-23-18)19(26)25-16-8-5-13(20)9-15(16)21/h3-11H,2H2,1H3,(H,23,24)(H,25,26)
InChIKeyLYXXGRFOQSEEHZ-UHFFFAOYSA-N
XLogP4.31
TPSA66.91 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500354.36
LogP ≤ 54.31
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

5-(3,4-dichloroanilino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide
CID 109294492
5-(4-ethylanilino)-N-[(4-fluorophenyl)methyl]pyrazine-2-carboxamide
CID 109281597
5-(2,6-difluoroanilino)-N-(2,4-difluorophenyl)pyrazine-2-carboxamide
CID 109294504
N-(2,4-difluorophenyl)-5-[2-(4-fluorophenyl)ethylamino]pyrazine-2-carboxamide
CID 109284577
N-(2,4-difluorophenyl)-5-(2-propan-2-ylanilino)pyrazine-2-carboxamide
CID 109291993
6-(2,4-difluoroanilino)-N-(4-ethylphenyl)pyrimidine-4-carboxamide
CID 109357398
4-N-(2,4-difluorophenyl)-2-N-(4-ethylphenyl)pyridine-2,4-dicarboxamide
CID 109092315
N-(2,5-dichlorophenyl)-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
CID 109294510
5-anilino-N-(2,4-difluorophenyl)pyridine-2-carboxamide
CID 109197129
N-(4-cyanophenyl)-5-(2,4-difluoroanilino)pyrazine-2-carboxamide
CID 109294517
N-(2,4-difluorophenyl)-5-(2-propan-2-yloxyanilino)pyrazine-2-carboxamide
CID 109293851
5-(2,4-difluoroanilino)-N-(2,4,6-trimethylphenyl)pyrazine-2-carboxamide
CID 109292112

Frequently Asked Questions

What is the IUPAC name of N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide?
The IUPAC name of N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide (CID 109291695) is N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide.
What is the SMILES notation for N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide?
The canonical SMILES for N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide is CCc1ccc(Nc2cnc(C(=O)Nc3ccc(F)cc3F)cn2)cc1.
What is the InChIKey of N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide?
The InChIKey is LYXXGRFOQSEEHZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16F2N4O/c1-2-12-3-6-14(7-4-12)24-18-11-22-17(10-23-18)19(26)25-16-8-5-13(20)9-15(16)21/h3-11H,2H2,1H3,(H,23,24)(H,25,26).
What are the key properties of N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide?
N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide has a molecular weight of 354.36 g/mol, XLogP of 4.31, 5 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2,4-difluorophenyl)-5-(4-ethylanilino)pyrazine-2-carboxamide is sourced from PubChem (CID 109291695), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).