4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine

C18H20N6S — CID 110093864

IUPAC4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine
SMILESCc1csc(Nc2cccc(C3CCN(c4ncccn4)CC3)n2)n1
InChIInChI=1S/C18H20N6S/c1-13-12-25-18(21-13)23-16-5-2-4-15(22-16)14-6-10-24(11-7-14)17-19-8-3-9-20-17/h2-5,8-9,12,14H,6-7,10-11H2,1H3,(H,21,22,23)
InChIKeyOLPDLGGCPDEFPE-UHFFFAOYSA-N
MW352.47 g/mol
LogP3.76
Rot. Bonds4

About 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine

4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine (PubChem CID 110093864) has the molecular formula C18H20N6S and a molecular weight of 352.47 g/mol. Its IUPAC name is 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine.

Molecular Properties

Compound Name4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine
PubChem CID110093864
Molecular FormulaC18H20N6S
Molecular Weight352.47 g/mol
Exact Mass352.15
IUPAC Name4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine
SMILESCc1csc(Nc2cccc(C3CCN(c4ncccn4)CC3)n2)n1
InChIInChI=1S/C18H20N6S/c1-13-12-25-18(21-13)23-16-5-2-4-15(22-16)14-6-10-24(11-7-14)17-19-8-3-9-20-17/h2-5,8-9,12,14H,6-7,10-11H2,1H3,(H,21,22,23)
InChIKeyOLPDLGGCPDEFPE-UHFFFAOYSA-N
XLogP3.76
TPSA66.83 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500352.47
LogP ≤ 53.76
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

Analyze 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine with MolForge

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Related Compounds

2-amino-1-[4-[6-[(4-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]piperidin-1-yl]ethanone
CID 110095864
4-methyl-N-(6-pyrrolidin-2-yl-2-pyridinyl)-1,3-thiazol-2-amine
CID 73439798
2-[2-[6-[(4-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]ethanol
CID 110268824
2-hydroxy-1-[(2R)-2-[6-[(4-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]ethanone
CID 95835387
(2,4-dimethylpyrimidin-5-yl)-[(2R)-2-[6-[(4-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]methanone
CID 95835423
4-methyl-2-(4-pyrimidin-2-ylpiperazin-1-yl)-1,3-thiazole
CID 31981427
2-(4-methoxyphenyl)-2-methyl-1-[2-[6-[(4-methyl-1,3-thiazol-2-yl)amino]-2-pyridinyl]pyrrolidin-1-yl]propan-1-one
CID 110265442
2-[4-[2-(pyridin-2-ylamino)-1,3-thiazol-4-yl]piperidin-1-yl]propane-1,3-diol
CID 95823889
N-[6-[(3S)-1-ethylpyrrolidin-3-yl]-2-methylpyrimidin-4-yl]-4-methyl-1,3-thiazol-2-amine
CID 124985635
N-[1-(5-bromopyrimidin-2-yl)piperidin-4-yl]-4-methyl-1,3-thiazol-2-amine
CID 133481351
N,N,2-trimethyl-6-(1-pyrimidin-2-ylpiperidin-4-yl)pyrimidin-4-amine
CID 95824229
N-methyl-6-[1-(6-methylpyrimidin-4-yl)piperidin-4-yl]pyridin-2-amine
CID 95824306

Frequently Asked Questions

What is the IUPAC name of 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine?
The IUPAC name of 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine (CID 110093864) is 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine.
What is the SMILES notation for 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine?
The canonical SMILES for 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine is Cc1csc(Nc2cccc(C3CCN(c4ncccn4)CC3)n2)n1.
What is the InChIKey of 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine?
The InChIKey is OLPDLGGCPDEFPE-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20N6S/c1-13-12-25-18(21-13)23-16-5-2-4-15(22-16)14-6-10-24(11-7-14)17-19-8-3-9-20-17/h2-5,8-9,12,14H,6-7,10-11H2,1H3,(H,21,22,23).
What are the key properties of 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine?
4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine has a molecular weight of 352.47 g/mol, XLogP of 3.76, 4 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 4-methyl-N-[6-(1-pyrimidin-2-ylpiperidin-4-yl)-2-pyridinyl]-1,3-thiazol-2-amine is sourced from PubChem (CID 110093864), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).