1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione

C10H8FN3O3S — CID 112600165

IUPAC1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione
SMILESO=c1[nH]c(=O)n(-c2nc(C3CC3)cs2)c(O)c1F
InChIInChI=1S/C10H8FN3O3S/c11-6-7(15)13-9(17)14(8(6)16)10-12-5(3-18-10)4-1-2-4/h3-4,16H,1-2H2,(H,13,15,17)
InChIKeyRDWQAWCKQSLSNM-UHFFFAOYSA-N
MW269.26 g/mol
LogP0.70
Rot. Bonds2

About 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione

1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione (PubChem CID 112600165) has the molecular formula C10H8FN3O3S and a molecular weight of 269.26 g/mol. Its IUPAC name is 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione.

Molecular Properties

Compound Name1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione
PubChem CID112600165
Molecular FormulaC10H8FN3O3S
Molecular Weight269.26 g/mol
Exact Mass269.03
IUPAC Name1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione
SMILESO=c1[nH]c(=O)n(-c2nc(C3CC3)cs2)c(O)c1F
InChIInChI=1S/C10H8FN3O3S/c11-6-7(15)13-9(17)14(8(6)16)10-12-5(3-18-10)4-1-2-4/h3-4,16H,1-2H2,(H,13,15,17)
InChIKeyRDWQAWCKQSLSNM-UHFFFAOYSA-N
XLogP0.70
TPSA87.98 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500269.26
LogP ≤ 50.70
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

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Related Compounds

N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
CID 62490115
N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2-difluoroacetamide
CID 103515709
N-(4-cyclopropyl-1,3-thiazol-2-yl)-2,2,3,3-tetrafluoropropanamide
CID 103733185
5-Fluoro-6-hydroxy-1-(4-methyl-1,3-thiazol-2-yl)pyrimidine-2,4-dione
CID 112598818
5-Fluoro-6-hydroxy-1-(4-propan-2-yl-1,3-thiazol-2-yl)pyrimidine-2,4-dione
CID 112599850
1-(4-Tert-butyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione
CID 112600069
6-chloro-5-fluoro-3-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-pyrimidine-2,4-dione
CID 113404560
6-chloro-3-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione
CID 113404614
N-(4-cyclopropyl-1,3-thiazol-2-yl)acetamide
CID 21179589
N-(4-cyclopropyl-1,3-thiazol-2-yl)-2-methylprop-2-enamide
CID 91015818
1-(4-Cyclopropyl-1,3-thiazol-2-yl)pyrrole-2,5-dione
CID 61482262
N-(4-cyclopropyl-1,3-thiazol-2-yl)prop-2-enamide
CID 61482354

Frequently Asked Questions

What is the IUPAC name of 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione?
The IUPAC name of 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione (CID 112600165) is 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione.
What is the SMILES notation for 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione?
The canonical SMILES for 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione is O=c1[nH]c(=O)n(-c2nc(C3CC3)cs2)c(O)c1F.
What is the InChIKey of 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione?
The InChIKey is RDWQAWCKQSLSNM-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H8FN3O3S/c11-6-7(15)13-9(17)14(8(6)16)10-12-5(3-18-10)4-1-2-4/h3-4,16H,1-2H2,(H,13,15,17).
What are the key properties of 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione?
1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione has a molecular weight of 269.26 g/mol, XLogP of 0.70, 2 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(4-cyclopropyl-1,3-thiazol-2-yl)-5-fluoro-6-hydroxypyrimidine-2,4-dione is sourced from PubChem (CID 112600165), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).