8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

C23H24F2N6O2 — CID 118145005

About 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 118145005) has the molecular formula C23H24F2N6O2 and a molecular weight of 454.48 g/mol. Its IUPAC name is 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• PubChem CID: 118145005
• Molecular Formula: C23H24F2N6O2
• Molecular Weight: 454.48 g/mol
• Exact Mass: 454.19
• IUPAC Name: 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• SMILES: Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)Nc1cnn(CCN(C)C)c1
• InChI: InChI=1S/C23H24F2N6O2/c1-15-21(23(32)28-16-12-26-30(13-16)11-10-29(2)3)31-9-5-8-20(22(31)27-15)33-14-17-18(24)6-4-7-19(17)25/h4-9,12-13H,10-11,14H2,1-3H3,(H,28,32)
• InChIKey: GRGDBPNEGARJMS-UHFFFAOYSA-N
• XLogP: 3.51
• TPSA: 76.69 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 7
• Rotatable Bonds: 8
• Heavy Atoms: 33
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	454.48
LogP ≤ 5	3.51
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CID 118145005) is 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

What is the SMILES notation for 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The canonical SMILES for 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)Nc1cnn(CCN(C)C)c1.

What is the InChIKey of 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The InChIKey is GRGDBPNEGARJMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H24F2N6O2/c1-15-21(23(32)28-16-12-26-30(13-16)11-10-29(2)3)31-9-5-8-20(22(31)27-15)33-14-17-18(24)6-4-7-19(17)25/h4-9,12-13H,10-11,14H2,1-3H3,(H,28,32).

What are the key properties of 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 454.48 g/mol, XLogP of 3.51, 8 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[(2,6-difluorophenyl)methoxy]-N-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 118145005), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).