8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

C25H24F2N4O4 — CID 118321089

About 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide

8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 118321089) has the molecular formula C25H24F2N4O4 and a molecular weight of 482.49 g/mol. Its IUPAC name is 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• PubChem CID: 118321089
• Molecular Formula: C25H24F2N4O4
• Molecular Weight: 482.49 g/mol
• Exact Mass: 482.18
• IUPAC Name: 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide
• SMILES: Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NCc1cccnc1[C@@H](O)[C@@H](C)O
• InChI: InChI=1S/C25H24F2N4O4/c1-14-22(25(34)29-12-16-6-4-10-28-21(16)23(33)15(2)32)31-11-5-9-20(24(31)30-14)35-13-17-18(26)7-3-8-19(17)27/h3-11,15,23,32-33H,12-13H2,1-2H3,(H,29,34)/t15-,23+/m1/s1
• InChIKey: FWRIBOULXFTNMW-CMJOXMDJSA-N
• XLogP: 3.24
• TPSA: 108.98 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 7
• Rotatable Bonds: 8
• Heavy Atoms: 35
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	482.49
LogP ≤ 5	3.24
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CID 118321089) is 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

What is the SMILES notation for 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The canonical SMILES for 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NCc1cccnc1[C@@H](O)[C@@H](C)O.

What is the InChIKey of 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

The InChIKey is FWRIBOULXFTNMW-CMJOXMDJSA-N. The full InChI is InChI=1S/C25H24F2N4O4/c1-14-22(25(34)29-12-16-6-4-10-28-21(16)23(33)15(2)32)31-11-5-9-20(24(31)30-14)35-13-17-18(26)7-3-8-19(17)27/h3-11,15,23,32-33H,12-13H2,1-2H3,(H,29,34)/t15-,23+/m1/s1.

What are the key properties of 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide?

8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 482.49 g/mol, XLogP of 3.24, 8 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[(2,6-difluorophenyl)methoxy]-N-[[2-[(1R,2R)-1,2-dihydroxypropyl]-3-pyridinyl]methyl]-2-methylimidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 118321089), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).