2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide

C7H5F3N2O2 — CID 118808984

IUPAC2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide
SMILESNC(=O)c1c(O)cnc(C(F)F)c1F
InChIInChI=1S/C7H5F3N2O2/c8-4-3(7(11)14)2(13)1-12-5(4)6(9)10/h1,6,13H,(H2,11,14)
InChIKeyKXDRMUARJJJKSY-UHFFFAOYSA-N
MW206.12 g/mol
LogP0.96
Rot. Bonds2

About 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide

2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide (PubChem CID 118808984) has the molecular formula C7H5F3N2O2 and a molecular weight of 206.12 g/mol. Its IUPAC name is 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide.

Molecular Properties

Compound Name2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide
PubChem CID118808984
Molecular FormulaC7H5F3N2O2
Molecular Weight206.12 g/mol
Exact Mass206.03
IUPAC Name2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide
SMILESNC(=O)c1c(O)cnc(C(F)F)c1F
InChIInChI=1S/C7H5F3N2O2/c8-4-3(7(11)14)2(13)1-12-5(4)6(9)10/h1,6,13H,(H2,11,14)
InChIKeyKXDRMUARJJJKSY-UHFFFAOYSA-N
XLogP0.96
TPSA76.21 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500206.12
LogP ≤ 50.96
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

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Related Compounds

2-(difluoromethyl)-5-hydroxy-4-methylpyridine-3-carboxamide
CID 118826495
4-amino-6-(difluoromethyl)-5-fluoropyridin-3-ol
CID 118806774
2-amino-3-(difluoromethyl)-5-hydroxypyridine-4-carboxamide
CID 119009453
4-amino-2-(difluoromethyl)-5-fluoropyridine-3-carboxamide
CID 118817125
3-(aminomethyl)-2-(difluoromethyl)-5-hydroxypyridine-4-carboxylic acid
CID 133102626
2-(difluoromethyl)-3-fluoro-5-iodopyridine-4-carboxylic acid
CID 118837172
6-(difluoromethyl)-5-fluoro-4-(hydroxymethyl)pyridin-3-ol
CID 130079568
ethyl 2-(difluoromethyl)-3,5-dihydroxypyridine-4-carboxylate
CID 133093322
2-(difluoromethyl)-5-methoxy-4-methylpyridine-3-carboxamide
CID 118809416
2-(difluoromethyl)-3,5-dimethoxypyridine-4-carboxamide
CID 118837482
6-(difluoromethyl)-5-hydroxy-4-methylpyridine-3-carboxamide
CID 130084161
4-bromo-2-(difluoromethyl)-5-hydroxypyridine-3-carbonyl chloride
CID 130110583

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide?
The IUPAC name of 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide (CID 118808984) is 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide.
What is the SMILES notation for 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide?
The canonical SMILES for 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide is NC(=O)c1c(O)cnc(C(F)F)c1F.
What is the InChIKey of 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide?
The InChIKey is KXDRMUARJJJKSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C7H5F3N2O2/c8-4-3(7(11)14)2(13)1-12-5(4)6(9)10/h1,6,13H,(H2,11,14).
What are the key properties of 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide?
2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide has a molecular weight of 206.12 g/mol, XLogP of 0.96, 2 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethyl)-3-fluoro-5-hydroxypyridine-4-carboxamide is sourced from PubChem (CID 118808984), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).