4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide

C8H8F2N2O3 — CID 118829275

IUPAC4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide
SMILESCOc1cc(C(F)F)c(O)c(C(N)=O)n1
InChIInChI=1S/C8H8F2N2O3/c1-15-4-2-3(7(9)10)6(13)5(12-4)8(11)14/h2,7,13H,1H3,(H2,11,14)
InChIKeyUSENDJPMWCLDLC-UHFFFAOYSA-N
MW218.16 g/mol
LogP0.83
Rot. Bonds3

About 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide

4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide (PubChem CID 118829275) has the molecular formula C8H8F2N2O3 and a molecular weight of 218.16 g/mol. Its IUPAC name is 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide.

Molecular Properties

Compound Name4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide
PubChem CID118829275
Molecular FormulaC8H8F2N2O3
Molecular Weight218.16 g/mol
Exact Mass218.05
IUPAC Name4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide
SMILESCOc1cc(C(F)F)c(O)c(C(N)=O)n1
InChIInChI=1S/C8H8F2N2O3/c1-15-4-2-3(7(9)10)6(13)5(12-4)8(11)14/h2,7,13H,1H3,(H2,11,14)
InChIKeyUSENDJPMWCLDLC-UHFFFAOYSA-N
XLogP0.83
TPSA85.44 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms15
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500218.16
LogP ≤ 50.83
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

4-(difluoromethyl)-6-methoxy-3-methylpyridine-2-carboxamide
CID 118840796
4-(difluoromethyl)-2-iodo-6-methoxypyridin-3-ol
CID 118852158
4-(difluoromethyl)-6-methoxy-3-methylpyridine-2-carbonyl chloride
CID 118835181
4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-sulfonyl chloride
CID 118800764
4-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine-2-carboxylic acid
CID 118834996
3-(difluoromethyl)-5-methoxy-6-methylpyridine-2-carboxamide
CID 133098966
ethyl 4-(difluoromethyl)-3-hydroxy-6-(trifluoromethoxy)pyridine-2-carboxylate
CID 134660628
methyl 3-cyano-4-(difluoromethyl)-6-methoxypyridine-2-carboxylate
CID 134676477
2-(difluoromethyl)-3-iodo-6-methoxypyridine-4-carboxamide
CID 118837244
6-chloro-3-(difluoromethyl)-5-methoxypyridine-2-carboxamide
CID 119005525
6-bromo-3-(difluoromethyl)-5-methoxypyridine-2-carboxamide
CID 118992492
ethyl 4-(difluoromethyl)-2-iodo-6-methoxypyridine-3-carboxylate
CID 133102053

Frequently Asked Questions

What is the IUPAC name of 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide?
The IUPAC name of 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide (CID 118829275) is 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide.
What is the SMILES notation for 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide?
The canonical SMILES for 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide is COc1cc(C(F)F)c(O)c(C(N)=O)n1.
What is the InChIKey of 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide?
The InChIKey is USENDJPMWCLDLC-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H8F2N2O3/c1-15-4-2-3(7(9)10)6(13)5(12-4)8(11)14/h2,7,13H,1H3,(H2,11,14).
What are the key properties of 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide?
4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide has a molecular weight of 218.16 g/mol, XLogP of 0.83, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(difluoromethyl)-3-hydroxy-6-methoxypyridine-2-carboxamide is sourced from PubChem (CID 118829275), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).