1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine

C19H22F2N2O2 — CID 120753405

IUPAC1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine
SMILESCOc1ccccc1C1CNCCN1Cc1ccccc1OC(F)F
InChIInChI=1S/C19H22F2N2O2/c1-24-18-9-5-3-7-15(18)16-12-22-10-11-23(16)13-14-6-2-4-8-17(14)25-19(20)21/h2-9,16,19,22H,10-13H2,1H3
InChIKeyLIKNLHNPBNNNPT-UHFFFAOYSA-N
MW348.39 g/mol
LogP3.44
Rot. Bonds6

About 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine

1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine (PubChem CID 120753405) has the molecular formula C19H22F2N2O2 and a molecular weight of 348.39 g/mol. Its IUPAC name is 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine.

Molecular Properties

Compound Name1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine
PubChem CID120753405
Molecular FormulaC19H22F2N2O2
Molecular Weight348.39 g/mol
Exact Mass348.16
IUPAC Name1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine
SMILESCOc1ccccc1C1CNCCN1Cc1ccccc1OC(F)F
InChIInChI=1S/C19H22F2N2O2/c1-24-18-9-5-3-7-15(18)16-12-22-10-11-23(16)13-14-6-2-4-8-17(14)25-19(20)21/h2-9,16,19,22H,10-13H2,1H3
InChIKeyLIKNLHNPBNNNPT-UHFFFAOYSA-N
XLogP3.44
TPSA33.73 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds6
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500348.39
LogP ≤ 53.44
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

1-[[3-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine
CID 120754169
2-[2-(difluoromethoxy)phenyl]-1-[2-(2-methoxyphenyl)piperazin-1-yl]ethanone
CID 120732889
1-[(2,4-difluorophenyl)methyl]-2-(2-methoxyphenyl)piperazine;hydrochloride
CID 120753939
1-[[2-(difluoromethoxy)phenyl]methyl]-2-pyridin-3-ylpiperazine
CID 120754669
1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-2-(2-methoxyphenyl)piperazine;hydrochloride
CID 120767334
1-[(1,5-dimethylpyrazol-4-yl)methyl]-2-(2-methoxyphenyl)piperazine
CID 120767394
1-[[1-(difluoromethyl)imidazol-2-yl]methyl]-2-(2-methoxyphenyl)piperazine
CID 120753443
N-[4-(difluoromethoxy)phenyl]-2-[2-(2-methoxyphenyl)piperazin-1-yl]acetamide
CID 120753715
(2R)-1-[(2-methoxyphenyl)methyl]-2-methylpiperazine
CID 82755826
1-(2-methoxyethyl)-2-(2-methoxyphenyl)piperazine;hydrochloride
CID 120753905
2-(2-methoxyphenyl)-1-[(2-methoxy-5-pyridin-4-ylphenyl)methyl]piperazine
CID 120767270
4-[[2-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-methylquinoline;dihydrochloride
CID 120753959

Frequently Asked Questions

What is the IUPAC name of 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine?
The IUPAC name of 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine (CID 120753405) is 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine.
What is the SMILES notation for 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine?
The canonical SMILES for 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine is COc1ccccc1C1CNCCN1Cc1ccccc1OC(F)F.
What is the InChIKey of 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine?
The InChIKey is LIKNLHNPBNNNPT-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H22F2N2O2/c1-24-18-9-5-3-7-15(18)16-12-22-10-11-23(16)13-14-6-2-4-8-17(14)25-19(20)21/h2-9,16,19,22H,10-13H2,1H3.
What are the key properties of 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine?
1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine has a molecular weight of 348.39 g/mol, XLogP of 3.44, 6 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[[2-(difluoromethoxy)phenyl]methyl]-2-(2-methoxyphenyl)piperazine is sourced from PubChem (CID 120753405), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).