Tizaterkib

Name: Tizaterkib — Molecular Data
Creator: MolForge
License: https://creativecommons.org/publicdomain/zero/1.0/

C₂₄H₂₄F₂N₈O₂ — CID 129116690

Data last refreshed: 2026-04-15 (MolForge compound catalog, from PubChem)

IUPAC(6R)-7-[(3,4-difluorophenyl)methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one

SMILESCOC[C@H]1Cn2cc(-c3nc(Nc4ccnn4C)ncc3C)nc2C(=O)N1Cc1ccc(F)c(F)c1

InChIInChI=1S/C24H24F2N8O2/c1-14-9-27-24(30-20-6-7-28-32(20)2)31-21(14)19-12-33-11-16(13-36-3)34(23(35)22(33)29-19)10-15-4-5-17(25)18(26)8-15/h4-9,12,16H,10-11,13H2,1-3H3,(H,27,30,31)/t16-/m1/s1

InChIKeyHVIGNZUDBVLTLU-MRXNPFEDSA-N

MW494.51 g/mol

LogP3.07

Rot. Bonds7

About Tizaterkib

Tizaterkib (PubChem CID 129116690) has the molecular formula C₂₄H₂₄F₂N₈O₂ and a molecular weight of 494.51 g/mol. Its IUPAC name is (6R)-7-[(3,4-difluorophenyl)methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one.

Molecular Properties

Compound Name	Tizaterkib
PubChem CID	129116690
Molecular Formula	C₂₄H₂₄F₂N₈O₂
Molecular Weight	494.51 g/mol
Exact Mass	494.20
IUPAC Name	(6R)-7-[(3,4-difluorophenyl)methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one
SMILES	COC[C@H]1Cn2cc(-c3nc(Nc4ccnn4C)ncc3C)nc2C(=O)N1Cc1ccc(F)c(F)c1
InChI	InChI=1S/C24H24F2N8O2/c1-14-9-27-24(30-20-6-7-28-32(20)2)31-21(14)19-12-33-11-16(13-36-3)34(23(35)22(33)29-19)10-15-4-5-17(25)18(26)8-15/h4-9,12,16H,10-11,13H2,1-3H3,(H,27,30,31)/t16-/m1/s1
InChIKey	HVIGNZUDBVLTLU-MRXNPFEDSA-N
XLogP	3.07
TPSA	102.99 Å²
H-Bond Donors	1
H-Bond Acceptors	9
Rotatable Bonds	7
Heavy Atoms	36
Complexity	—

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	494.51
LogP ≤ 5	3.07
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	9

Frequently Asked Questions

What is the IUPAC name of Tizaterkib?

The IUPAC name of Tizaterkib (CID 129116690) is (6R)-7-[(3,4-difluorophenyl)methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one.

What is the SMILES notation for Tizaterkib?

The canonical SMILES for Tizaterkib is COC[C@H]1Cn2cc(-c3nc(Nc4ccnn4C)ncc3C)nc2C(=O)N1Cc1ccc(F)c(F)c1.

What is the InChIKey of Tizaterkib?

The InChIKey is HVIGNZUDBVLTLU-MRXNPFEDSA-N. The full InChI is InChI=1S/C24H24F2N8O2/c1-14-9-27-24(30-20-6-7-28-32(20)2)31-21(14)19-12-33-11-16(13-36-3)34(23(35)22(33)29-19)10-15-4-5-17(25)18(26)8-15/h4-9,12,16H,10-11,13H2,1-3H3,(H,27,30,31)/t16-/m1/s1.

What are the key properties of Tizaterkib?

Tizaterkib has a molecular weight of 494.51 g/mol, XLogP of 3.07, 7 rotatable bonds, 1 hydrogen bond donors, and 9 hydrogen bond acceptors.

Where does this data come from?

All data for Tizaterkib is sourced from PubChem (CID 129116690), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

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Sources

PubChem CID 129116690 — identifiers, structure, computed properties (public domain)

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