N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide

C14H16N4OS — CID 133273014

IUPACN-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide
SMILESO=C(NC1CCN(c2cnccn2)CC1)c1ccsc1
InChIInChI=1S/C14H16N4OS/c19-14(11-3-8-20-10-11)17-12-1-6-18(7-2-12)13-9-15-4-5-16-13/h3-5,8-10,12H,1-2,6-7H2,(H,17,19)
InChIKeyDGWCJSJTLGRSNP-UHFFFAOYSA-N
MW288.38 g/mol
LogP1.94
Rot. Bonds3

About N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide

N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide (PubChem CID 133273014) has the molecular formula C14H16N4OS and a molecular weight of 288.38 g/mol. Its IUPAC name is N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide.

Molecular Properties

Compound NameN-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide
PubChem CID133273014
Molecular FormulaC14H16N4OS
Molecular Weight288.38 g/mol
Exact Mass288.10
IUPAC NameN-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide
SMILESO=C(NC1CCN(c2cnccn2)CC1)c1ccsc1
InChIInChI=1S/C14H16N4OS/c19-14(11-3-8-20-10-11)17-12-1-6-18(7-2-12)13-9-15-4-5-16-13/h3-5,8-10,12H,1-2,6-7H2,(H,17,19)
InChIKeyDGWCJSJTLGRSNP-UHFFFAOYSA-N
XLogP1.94
TPSA58.12 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500288.38
LogP ≤ 51.94
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Related Compounds

N-[1-(6-methylpyrimidin-4-yl)piperidin-4-yl]thiophene-3-carboxamide
CID 133298747
N-[1-(1-pyrazin-2-ylpiperidine-4-carbonyl)piperidin-4-yl]benzamide
CID 38795279
N-[1-(4-methoxypyrimidin-2-yl)piperidin-4-yl]thiophene-3-carboxamide
CID 133273038
N-[(3S)-1-(3-methoxypyrazin-2-yl)pyrrolidin-3-yl]thiophene-3-carboxamide
CID 95107609
N-[1-(3-nitro-2-pyridinyl)piperidin-4-yl]thiophene-3-carboxamide
CID 133273015
3-methyl-N-(1-pyrazin-2-ylpiperidin-4-yl)imidazo[4,5-b]pyridine-6-carboxamide
CID 176501776
6-oxo-N-(1-pyrazin-2-ylpiperidin-4-yl)-1H-pyrazine-3-carboxamide
CID 118792476
4-chloro-N-(1-pyrazin-2-ylpiperidin-4-yl)-1H-pyrrole-2-carboxamide
CID 119072365
N-[1-(1,2,5-thiadiazol-3-yl)piperidin-4-yl]-4-thiophen-3-ylbenzamide
CID 131702121
1-pyrazin-2-yl-N-(1-pyrimidin-2-ylpiperidin-4-yl)piperidine-4-carboxamide
CID 23609685
N-[1-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]thiophene-3-carboxamide
CID 128948618
N-[(3R)-1-pyrazin-2-ylpiperidin-3-yl]-4-pyrrolidin-1-ylbenzamide
CID 99990589

Frequently Asked Questions

What is the IUPAC name of N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide?
The IUPAC name of N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide (CID 133273014) is N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide.
What is the SMILES notation for N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide?
The canonical SMILES for N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide is O=C(NC1CCN(c2cnccn2)CC1)c1ccsc1.
What is the InChIKey of N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide?
The InChIKey is DGWCJSJTLGRSNP-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H16N4OS/c19-14(11-3-8-20-10-11)17-12-1-6-18(7-2-12)13-9-15-4-5-16-13/h3-5,8-10,12H,1-2,6-7H2,(H,17,19).
What are the key properties of N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide?
N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide has a molecular weight of 288.38 g/mol, XLogP of 1.94, 3 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-(1-pyrazin-2-ylpiperidin-4-yl)thiophene-3-carboxamide is sourced from PubChem (CID 133273014), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).