1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one

C16H20N4O2 — CID 133447156

IUPAC1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one
SMILESCCn1ccnc(N2CCN(c3ccccc3O)CC2)c1=O
InChIInChI=1S/C16H20N4O2/c1-2-18-8-7-17-15(16(18)22)20-11-9-19(10-12-20)13-5-3-4-6-14(13)21/h3-8,21H,2,9-12H2,1H3
InChIKeyRHTVCNWTQYIPEV-UHFFFAOYSA-N
MW300.36 g/mol
LogP1.30
Rot. Bonds3

About 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one

1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one (PubChem CID 133447156) has the molecular formula C16H20N4O2 and a molecular weight of 300.36 g/mol. Its IUPAC name is 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one.

Molecular Properties

Compound Name1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one
PubChem CID133447156
Molecular FormulaC16H20N4O2
Molecular Weight300.36 g/mol
Exact Mass300.16
IUPAC Name1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one
SMILESCCn1ccnc(N2CCN(c3ccccc3O)CC2)c1=O
InChIInChI=1S/C16H20N4O2/c1-2-18-8-7-17-15(16(18)22)20-11-9-19(10-12-20)13-5-3-4-6-14(13)21/h3-8,21H,2,9-12H2,1H3
InChIKeyRHTVCNWTQYIPEV-UHFFFAOYSA-N
XLogP1.30
TPSA61.60 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds3
Heavy Atoms22
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500300.36
LogP ≤ 51.30
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

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Related Compounds

3-[4-(2-methylphenyl)piperazin-1-yl]-1-(2-methylpropyl)pyrazin-2-one
CID 133424216
1-ethyl-3-[4-(methylamino)piperidin-1-yl]pyrazin-2-one
CID 62939421
4-(4-ethyl-3-oxopyrazin-2-yl)-N-methylpiperazine-1-sulfonamide
CID 154736074
1-ethyl-3-[4-(4-methoxy-2-pyridinyl)piperazin-1-yl]pyrazin-2-one
CID 146125355
3-[4-(2-aminoethyl)-1,4-diazepan-1-yl]-1-ethylpyrazin-2-one
CID 55219868
1-[(3S)-3,4-dihydro-2H-chromen-3-yl]-3-[1-(4-ethyl-3-oxopyrazin-2-yl)piperidin-4-yl]urea
CID 129347080
3-(3-aminopyrrolidin-1-yl)-1-ethylpyrazin-2-one
CID 62928142
1-ethyl-3-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]pyrazin-2-one
CID 136520233
3-(2,6-dimethylmorpholin-4-yl)-1-ethylpyrazin-2-one
CID 133446960
4-ethyl-N-[1-(4-ethyl-3-oxopyrazin-2-yl)piperidin-4-yl]benzamide
CID 129000920
3-(3-chloropiperidin-1-yl)-1-ethylpyrazin-2-one
CID 63392087
3-piperazin-1-yl-1-propylpyrazin-2-one
CID 62938367

Frequently Asked Questions

What is the IUPAC name of 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one?
The IUPAC name of 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one (CID 133447156) is 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one.
What is the SMILES notation for 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one?
The canonical SMILES for 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one is CCn1ccnc(N2CCN(c3ccccc3O)CC2)c1=O.
What is the InChIKey of 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one?
The InChIKey is RHTVCNWTQYIPEV-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H20N4O2/c1-2-18-8-7-17-15(16(18)22)20-11-9-19(10-12-20)13-5-3-4-6-14(13)21/h3-8,21H,2,9-12H2,1H3.
What are the key properties of 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one?
1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one has a molecular weight of 300.36 g/mol, XLogP of 1.30, 3 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 1-ethyl-3-[4-(2-hydroxyphenyl)piperazin-1-yl]pyrazin-2-one is sourced from PubChem (CID 133447156), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).