2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide

C19H16N6O2S — CID 134564863

IUPAC2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
SMILESCC(C=O)c1c(C(N)=O)cc(-c2cnn3ccc(-c4cccs4)nc23)nc1N
InChIInChI=1S/C19H16N6O2S/c1-10(9-26)16-11(18(21)27)7-14(23-17(16)20)12-8-22-25-5-4-13(24-19(12)25)15-3-2-6-28-15/h2-10H,1H3,(H2,20,23)(H2,21,27)
InChIKeyUZIJLPHCYYSYGI-UHFFFAOYSA-N
MW392.44 g/mol
LogP2.50
Rot. Bonds5

About 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide

2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide (PubChem CID 134564863) has the molecular formula C19H16N6O2S and a molecular weight of 392.44 g/mol. Its IUPAC name is 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide.

Molecular Properties

Compound Name2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
PubChem CID134564863
Molecular FormulaC19H16N6O2S
Molecular Weight392.44 g/mol
Exact Mass392.11
IUPAC Name2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
SMILESCC(C=O)c1c(C(N)=O)cc(-c2cnn3ccc(-c4cccs4)nc23)nc1N
InChIInChI=1S/C19H16N6O2S/c1-10(9-26)16-11(18(21)27)7-14(23-17(16)20)12-8-22-25-5-4-13(24-19(12)25)15-3-2-6-28-15/h2-10H,1H3,(H2,20,23)(H2,21,27)
InChIKeyUZIJLPHCYYSYGI-UHFFFAOYSA-N
XLogP2.50
TPSA129.26 Ų
H-Bond Donors2
H-Bond Acceptors8
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500392.44
LogP ≤ 52.50
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 108

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'aldehyde', 'substructure': 'N/A'}

Analyze 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-N-[(2S)-2-(diethylamino)propyl]-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539713
N-[(2S)-2-(diethylamino)propyl]-2-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539764
N-[(2S)-2-(diethylamino)propyl]-2-(methylamino)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134540119
2-[methyl(methylsulfanyl)amino]-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carbaldehyde
CID 134574579
N-[(2S)-2-(diethylamino)propyl]-2-(3,3-difluoroazetidin-1-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539611
N-[(2S)-2-(diethylamino)propyl]-2-(2-methoxyethoxy)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539892
N-[2-(diethylamino)propyl]-2-(ethylsulfonylamino)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539928
N-[2-(diethylamino)propyl]-2-(ethylsulfanylamino)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134574408
N-(2-aminopropyl)-2-(azetidin-1-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134574578
N-[(2S)-2-(diethylamino)propyl]-2-(1,3-oxazol-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide
CID 134539753
N-[2-(diethylamino)propyl]-2-oxo-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)-1H-pyridine-4-carboxamide
CID 134574673
N-[4-[(4S)-4-(diethylamino)pentanoyl]-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)-2-pyridinyl]-2-methylpropanamide
CID 157404362

Frequently Asked Questions

What is the IUPAC name of 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide?
The IUPAC name of 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide (CID 134564863) is 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide.
What is the SMILES notation for 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide?
The canonical SMILES for 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide is CC(C=O)c1c(C(N)=O)cc(-c2cnn3ccc(-c4cccs4)nc23)nc1N.
What is the InChIKey of 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide?
The InChIKey is UZIJLPHCYYSYGI-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16N6O2S/c1-10(9-26)16-11(18(21)27)7-14(23-17(16)20)12-8-22-25-5-4-13(24-19(12)25)15-3-2-6-28-15/h2-10H,1H3,(H2,20,23)(H2,21,27).
What are the key properties of 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide?
2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide has a molecular weight of 392.44 g/mol, XLogP of 2.50, 5 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-3-(1-oxopropan-2-yl)-6-(5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-4-carboxamide is sourced from PubChem (CID 134564863), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).