7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide

C24H28N4O4 — CID 135453449

IUPAC7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide
SMILESNC(=O)C1Cc2c(C3CCCNC3)cc(-c3c(O)cccc3OCC3CC3)nc2NC1=O
InChIInChI=1S/C24H28N4O4/c25-22(30)17-9-16-15(14-3-2-8-26-11-14)10-18(27-23(16)28-24(17)31)21-19(29)4-1-5-20(21)32-12-13-6-7-13/h1,4-5,10,13-14,17,26,29H,2-3,6-9,11-12H2,(H2,25,30)(H,27,28,31)
InChIKeyAYEHKYACNQAKGD-UHFFFAOYSA-N
MW436.51 g/mol
LogP2.31
Rot. Bonds6

About 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide

7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide (PubChem CID 135453449) has the molecular formula C24H28N4O4 and a molecular weight of 436.51 g/mol. Its IUPAC name is 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide.

Molecular Properties

Compound Name7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide
PubChem CID135453449
Molecular FormulaC24H28N4O4
Molecular Weight436.51 g/mol
Exact Mass436.21
IUPAC Name7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide
SMILESNC(=O)C1Cc2c(C3CCCNC3)cc(-c3c(O)cccc3OCC3CC3)nc2NC1=O
InChIInChI=1S/C24H28N4O4/c25-22(30)17-9-16-15(14-3-2-8-26-11-14)10-18(27-23(16)28-24(17)31)21-19(29)4-1-5-20(21)32-12-13-6-7-13/h1,4-5,10,13-14,17,26,29H,2-3,6-9,11-12H2,(H2,25,30)(H,27,28,31)
InChIKeyAYEHKYACNQAKGD-UHFFFAOYSA-N
XLogP2.31
TPSA126.57 Ų
H-Bond Donors4
H-Bond Acceptors6
Rotatable Bonds6
Heavy Atoms32
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500436.51
LogP ≤ 52.31
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 106

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'}

Analyze 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-piperidin-3-yl-1,4-dihydropyrido[2,3-d][1,3]oxazin-2-one;ethane
CID 142804159
N-cyclohexyl-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-1,4-dihydropyrido[2,3-d]pyrimidine-3-carboxamide
CID 135469661
tert-butyl 4-[6-carbamoyl-2-[2-(cyclopropylmethoxy)-6-[(4-methoxyphenyl)methoxy]phenyl]-7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl]piperidine-1-carboxylate;7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-4-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide;hydrochloride
CID 160657329
7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-1H-1,8-naphthyridine-3-carbonitrile;hydrochloride
CID 162335678
2-(2-amino-6-piperidin-3-ylpyrimidin-4-yl)-3-(cyclopropylmethoxy)phenol
CID 135481185
2-(2-amino-6-piperidin-3-ylpyrimidin-4-yl)-3-(cyclopropylmethoxy)phenol;hydrochloride
CID 142686934
2-amino-6-[[2-(cyclopropylmethoxy)-6-hydroxyphenyl]methyl]-4-piperidin-3-ylpyridine-3-carboxamide
CID 91403098
2-(2-amino-6-piperidin-3-ylpyrimidin-4-yl)-3-ethoxyphenol;dihydrochloride
CID 135618266
2-[6-amino-5-(hydroxymethyl)-4-piperidin-3-yl-2-pyridinyl]-3-(2,2-dimethylpropoxy)phenol
CID 135453352
2-amino-6-(2-hydroxy-6-phenylmethoxyphenyl)-4-piperidin-3-ylpyridine-3-carbaldehyde;hydrochloride
CID 135550596
3-[(4-tert-butylphenyl)methoxy]-2-(5,6-diamino-4-piperidin-3-yl-2-pyridinyl)phenol
CID 136634040
2-[6-amino-5-(hydroxymethyl)-4-piperidin-3-yl-2-pyridinyl]-3-phenylmethoxyphenol;methane
CID 157188587

Frequently Asked Questions

What is the IUPAC name of 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide?
The IUPAC name of 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide (CID 135453449) is 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide.
What is the SMILES notation for 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide?
The canonical SMILES for 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide is NC(=O)C1Cc2c(C3CCCNC3)cc(-c3c(O)cccc3OCC3CC3)nc2NC1=O.
What is the InChIKey of 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide?
The InChIKey is AYEHKYACNQAKGD-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H28N4O4/c25-22(30)17-9-16-15(14-3-2-8-26-11-14)10-18(27-23(16)28-24(17)31)21-19(29)4-1-5-20(21)32-12-13-6-7-13/h1,4-5,10,13-14,17,26,29H,2-3,6-9,11-12H2,(H2,25,30)(H,27,28,31).
What are the key properties of 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide?
7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide has a molecular weight of 436.51 g/mol, XLogP of 2.31, 6 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-2-oxo-5-piperidin-3-yl-3,4-dihydro-1H-1,8-naphthyridine-3-carboxamide is sourced from PubChem (CID 135453449), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).