2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile

C16H11N3OS — CID 136909232

IUPAC2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile
SMILESN#Cc1c(-c2cccs2)cc(-c2ccccc2O)nc1N
InChIInChI=1S/C16H11N3OS/c17-9-12-11(15-6-3-7-21-15)8-13(19-16(12)18)10-4-1-2-5-14(10)20/h1-8,20H,(H2,18,19)
InChIKeyVAJDZNLGRUZYKZ-UHFFFAOYSA-N
MW293.35 g/mol
LogP3.64
Rot. Bonds2

About 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile

2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile (PubChem CID 136909232) has the molecular formula C16H11N3OS and a molecular weight of 293.35 g/mol. Its IUPAC name is 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile.

Molecular Properties

Compound Name2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile
PubChem CID136909232
Molecular FormulaC16H11N3OS
Molecular Weight293.35 g/mol
Exact Mass293.06
IUPAC Name2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile
SMILESN#Cc1c(-c2cccs2)cc(-c2ccccc2O)nc1N
InChIInChI=1S/C16H11N3OS/c17-9-12-11(15-6-3-7-21-15)8-13(19-16(12)18)10-4-1-2-5-14(10)20/h1-8,20H,(H2,18,19)
InChIKeyVAJDZNLGRUZYKZ-UHFFFAOYSA-N
XLogP3.64
TPSA82.93 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds2
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500293.35
LogP ≤ 53.64
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

2-amino-6-(3-fluorophenyl)-4-thiophen-2-ylpyridine-3-carbonitrile
CID 5118720
2-amino-4-(2-hydroxyphenyl)-6-thiophen-3-ylpyridine-3-carbonitrile
CID 135924234
2-amino-4-(2,5-dimethoxyphenyl)-6-(2-hydroxyphenyl)pyridine-3-carbonitrile
CID 135496405
2-amino-4-(4-bromothiophen-2-yl)-6-(2-methylphenyl)pyridine-3-carbonitrile
CID 5230853
2-amino-4-(2,4-dimethoxyphenyl)-6-thiophen-2-ylpyridine-3-carbonitrile
CID 166594866
2-amino-4-(5-bromothiophen-2-yl)-6-(2-fluorophenyl)pyridine-3-carbonitrile
CID 5119571
2-(2-methylprop-2-enylsulfanyl)-6-phenyl-4-thiophen-2-ylpyridine-3-carbonitrile
CID 681158
2-[(3-cyano-6-naphthalen-2-yl-4-thiophen-2-yl-2-pyridinyl)sulfanyl]acetamide
CID 1010503
2-amino-6-oxo-1-phenyl-4-thiophen-2-ylpyridine-3-carbonitrile
CID 15362191
2-amino-4-(3-aminocyclohexyl)-6-(2-hydroxyphenyl)pyridine-3-carbonitrile;hydrochloride
CID 162321627
2-methyl-4-naphthalen-1-yl-6-thiophen-2-ylpyridine-3-carbonitrile
CID 15133262
6-methyl-2-pyrrolidin-1-yl-4-thiophen-2-ylpyridine-3-carbonitrile
CID 82092939

Frequently Asked Questions

What is the IUPAC name of 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile?
The IUPAC name of 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile (CID 136909232) is 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile.
What is the SMILES notation for 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile?
The canonical SMILES for 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile is N#Cc1c(-c2cccs2)cc(-c2ccccc2O)nc1N.
What is the InChIKey of 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile?
The InChIKey is VAJDZNLGRUZYKZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H11N3OS/c17-9-12-11(15-6-3-7-21-15)8-13(19-16(12)18)10-4-1-2-5-14(10)20/h1-8,20H,(H2,18,19).
What are the key properties of 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile?
2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile has a molecular weight of 293.35 g/mol, XLogP of 3.64, 2 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-6-(2-hydroxyphenyl)-4-thiophen-2-ylpyridine-3-carbonitrile is sourced from PubChem (CID 136909232), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).