5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide

C24H23FN8O2 — CID 138604994

IUPAC5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide
SMILESCNC(=O)c1ccc(C(=O)Nc2cc3cc(-c4cnn5c4CN(CCF)CC5)ncc3cn2)cn1
InChIInChI=1S/C24H23FN8O2/c1-26-24(35)19-3-2-15(10-27-19)23(34)31-22-9-16-8-20(28-11-17(16)12-29-22)18-13-30-33-7-6-32(5-4-25)14-21(18)33/h2-3,8-13H,4-7,14H2,1H3,(H,26,35)(H,29,31,34)
InChIKeyWEGPAKIWWAWPDS-UHFFFAOYSA-N
MW474.50 g/mol
LogP2.29
Rot. Bonds6

About 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide

5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide (PubChem CID 138604994) has the molecular formula C24H23FN8O2 and a molecular weight of 474.50 g/mol. Its IUPAC name is 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide.

Molecular Properties

Compound Name5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide
PubChem CID138604994
Molecular FormulaC24H23FN8O2
Molecular Weight474.50 g/mol
Exact Mass474.19
IUPAC Name5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide
SMILESCNC(=O)c1ccc(C(=O)Nc2cc3cc(-c4cnn5c4CN(CCF)CC5)ncc3cn2)cn1
InChIInChI=1S/C24H23FN8O2/c1-26-24(35)19-3-2-15(10-27-19)23(34)31-22-9-16-8-20(28-11-17(16)12-29-22)18-13-30-33-7-6-32(5-4-25)14-21(18)33/h2-3,8-13H,4-7,14H2,1H3,(H,26,35)(H,29,31,34)
InChIKeyWEGPAKIWWAWPDS-UHFFFAOYSA-N
XLogP2.29
TPSA117.93 Ų
H-Bond Donors2
H-Bond Acceptors8
Rotatable Bonds6
Heavy Atoms35
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500474.50
LogP ≤ 52.29
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 108

Analyze 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide with MolForge

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Related Compounds

N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
CID 138589109
4-fluoro-N-[6-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)-2,7-naphthyridin-3-yl]benzamide
CID 138590649
4-fluoro-N-[6-[1-methyl-5-(pyrrolidin-1-ylmethyl)pyrazol-4-yl]-2,7-naphthyridin-3-yl]benzamide
CID 138588716
2-(azetidin-3-yloxy)-N-[3-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-1,7-naphthyridin-6-yl]pyridine-4-carboxamide
CID 138589243
N-[1-[2-(azetidin-3-ylsulfanyl)-4-pyridinyl]ethenyl]-6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]isoquinolin-3-amine
CID 166787298
2-[2-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-1,6-naphthyridin-7-yl]-1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]ethanone
CID 159920114
6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-N-[1-[1-[[1-(trifluoromethyl)cyclopropyl]methyl]piperidin-4-yl]ethenyl]isoquinolin-3-amine
CID 166955083
2-(azetidin-3-yloxy)-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]cinnolin-3-yl]pyridine-4-carboxamide
CID 138590628
2-N-methyl-5-N-[2-(1-methyltriazol-4-yl)-1,6-naphthyridin-7-yl]pyridine-2,5-dicarboxamide
CID 138591714
3-[(4-methylpiperazin-1-yl)methyl]-N-[6-(1-methylpyrazol-4-yl)-2,7-naphthyridin-3-yl]benzamide
CID 138587575
4-(difluoromethoxy)-N-[6-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]-2,7-naphthyridin-3-yl]benzamide
CID 138587059
5-N-[6-[(Z)-1-[(Z)-1-aminopent-1-enyl]sulfanylprop-1-enyl]isoquinolin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide
CID 166787141

Frequently Asked Questions

What is the IUPAC name of 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide?
The IUPAC name of 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide (CID 138604994) is 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide.
What is the SMILES notation for 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide?
The canonical SMILES for 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide is CNC(=O)c1ccc(C(=O)Nc2cc3cc(-c4cnn5c4CN(CCF)CC5)ncc3cn2)cn1.
What is the InChIKey of 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide?
The InChIKey is WEGPAKIWWAWPDS-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H23FN8O2/c1-26-24(35)19-3-2-15(10-27-19)23(34)31-22-9-16-8-20(28-11-17(16)12-29-22)18-13-30-33-7-6-32(5-4-25)14-21(18)33/h2-3,8-13H,4-7,14H2,1H3,(H,26,35)(H,29,31,34).
What are the key properties of 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide?
5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide has a molecular weight of 474.50 g/mol, XLogP of 2.29, 6 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 5-N-[6-[5-(2-fluoroethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-3-yl]-2,7-naphthyridin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide is sourced from PubChem (CID 138604994), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).