(5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide

C24H26F2N4O5Si — CID 140774196

About (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide

(5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide (PubChem CID 140774196) has the molecular formula C24H26F2N4O5Si and a molecular weight of 516.58 g/mol. Its IUPAC name is (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide.

Molecular Properties

• Compound Name: (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
• PubChem CID: 140774196
• Molecular Formula: C24H26F2N4O5Si
• Molecular Weight: 516.58 g/mol
• Exact Mass: 516.16
• IUPAC Name: (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
• SMILES: COCc1ccc2c(n1)CCN(C(=O)c1cc(=O)[nH]o1)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1
• InChI: InChI=1S/C24H26F2N4O5Si/c1-34-12-13-5-6-15-18(27-13)7-8-30(24(33)19-11-20(31)29-35-19)21(15)23(32)28-14-9-16(25)22(17(26)10-14)36(2,3)4/h5-6,9-11,21H,7-8,12H2,1-4H3,(H,28,32)(H,29,31)/t21-/m1/s1
• InChIKey: GBFDIZBJNCRALT-OAQYLSRUSA-N
• XLogP: 2.71
• TPSA: 117.53 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 6
• Rotatable Bonds: 6
• Heavy Atoms: 36
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	516.58
LogP ≤ 5	2.71
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	6

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide?

The IUPAC name of (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide (CID 140774196) is (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide.

What is the SMILES notation for (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide?

The canonical SMILES for (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide is COCc1ccc2c(n1)CCN(C(=O)c1cc(=O)[nH]o1)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1.

What is the InChIKey of (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide?

The InChIKey is GBFDIZBJNCRALT-OAQYLSRUSA-N. The full InChI is InChI=1S/C24H26F2N4O5Si/c1-34-12-13-5-6-15-18(27-13)7-8-30(24(33)19-11-20(31)29-35-19)21(15)23(32)28-14-9-16(25)22(17(26)10-14)36(2,3)4/h5-6,9-11,21H,7-8,12H2,1-4H3,(H,28,32)(H,29,31)/t21-/m1/s1.

What are the key properties of (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide?

(5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide has a molecular weight of 516.58 g/mol, XLogP of 2.71, 6 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-(methoxymethyl)-6-(3-oxo-1,2-oxazole-5-carbonyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide is sourced from PubChem (CID 140774196), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).