6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide

C20H26N2O2Si — CID 140774274

IUPAC6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
SMILESCOc1ccc2c(c1)CCNC2C(=O)Nc1ccc([Si](C)(C)C)cc1
InChIInChI=1S/C20H26N2O2Si/c1-24-16-7-10-18-14(13-16)11-12-21-19(18)20(23)22-15-5-8-17(9-6-15)25(2,3)4/h5-10,13,19,21H,11-12H2,1-4H3,(H,22,23)
InChIKeyDSMNPZNIKHXOOS-UHFFFAOYSA-N
MW354.53 g/mol
LogP3.07
Rot. Bonds4

About 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide

6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide (PubChem CID 140774274) has the molecular formula C20H26N2O2Si and a molecular weight of 354.53 g/mol. Its IUPAC name is 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide.

Molecular Properties

Compound Name6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
PubChem CID140774274
Molecular FormulaC20H26N2O2Si
Molecular Weight354.53 g/mol
Exact Mass354.18
IUPAC Name6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
SMILESCOc1ccc2c(c1)CCNC2C(=O)Nc1ccc([Si](C)(C)C)cc1
InChIInChI=1S/C20H26N2O2Si/c1-24-16-7-10-18-14(13-16)11-12-21-19(18)20(23)22-15-5-8-17(9-6-15)25(2,3)4/h5-10,13,19,21H,11-12H2,1-4H3,(H,22,23)
InChIKeyDSMNPZNIKHXOOS-UHFFFAOYSA-N
XLogP3.07
TPSA50.36 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500354.53
LogP ≤ 53.07
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Analyze 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(4-tert-butyl-3-cyanophenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
CID 121321107
(6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-pyrrolidin-1-ylmethanone
CID 23128327
6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-ol;hydrochloride
CID 90423697
(1R)-N-[3,5-difluoro-4-(1-methoxy-2-methylpropan-2-yl)phenyl]-6-ethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamide;hydrochloride
CID 118622727
N-(3-fluoro-4-trimethylsilylphenyl)-2-methoxy-5,6,7,8-tetrahydro-1,6-naphthyridine-5-carboxamide
CID 140774100
N-phenyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamide;hydrochloride
CID 23333350
methyl N-[[4-[[(1S)-1,2,3,4-tetrahydroisoquinoline-1-carbonyl]amino]phenyl]methyl]carbamate
CID 140654603
N-(3-bromo-5-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
CID 107583487
(4-methoxyphenyl) 1,2,3,4-tetrahydroisoquinoline-1-carboxylate
CID 141338899
6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile
CID 102340504
methyl 6,13-dimethoxytricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxylate
CID 83985276
N-[4-(thiadiazol-4-yl)phenyl]-1,2,3,4-tetrahydroisoquinoline-1-carboxamide;hydrochloride
CID 86780202

Frequently Asked Questions

What is the IUPAC name of 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide?
The IUPAC name of 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide (CID 140774274) is 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide.
What is the SMILES notation for 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide?
The canonical SMILES for 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide is COc1ccc2c(c1)CCNC2C(=O)Nc1ccc([Si](C)(C)C)cc1.
What is the InChIKey of 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide?
The InChIKey is DSMNPZNIKHXOOS-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H26N2O2Si/c1-24-16-7-10-18-14(13-16)11-12-21-19(18)20(23)22-15-5-8-17(9-6-15)25(2,3)4/h5-10,13,19,21H,11-12H2,1-4H3,(H,22,23).
What are the key properties of 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide?
6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide has a molecular weight of 354.53 g/mol, XLogP of 3.07, 4 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 6-methoxy-N-(4-trimethylsilylphenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide is sourced from PubChem (CID 140774274), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).