(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran

C12H10F4O — CID 153410075

IUPAC(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran
SMILESFc1ccc(C2=CO[C@@H](C(F)F)CC2)c(F)c1
InChIInChI=1S/C12H10F4O/c13-8-2-3-9(10(14)5-8)7-1-4-11(12(15)16)17-6-7/h2-3,5-6,11-12H,1,4H2/t11-/m1/s1
InChIKeyFEUCAUDGGTXNNL-LLVKDONJSA-N
MW246.20 g/mol
LogP3.75
Rot. Bonds2

About (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran

(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran (PubChem CID 153410075) has the molecular formula C12H10F4O and a molecular weight of 246.20 g/mol. Its IUPAC name is (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran.

Molecular Properties

Compound Name(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran
PubChem CID153410075
Molecular FormulaC12H10F4O
Molecular Weight246.20 g/mol
Exact Mass246.07
IUPAC Name(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran
SMILESFc1ccc(C2=CO[C@@H](C(F)F)CC2)c(F)c1
InChIInChI=1S/C12H10F4O/c13-8-2-3-9(10(14)5-8)7-1-4-11(12(15)16)17-6-7/h2-3,5-6,11-12H,1,4H2/t11-/m1/s1
InChIKeyFEUCAUDGGTXNNL-LLVKDONJSA-N
XLogP3.75
TPSA9.23 Ų
H-Bond Donors
H-Bond Acceptors1
Rotatable Bonds2
Heavy Atoms17
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500246.20
LogP ≤ 53.75
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 101

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Related Compounds

2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran
CID 174959767
(2S)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran
CID 153410062
[(2R)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran-2-yl]methanol
CID 175232862
[(2S)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran-2-yl]methanol
CID 153410093
N-[[5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran-2-yl]methyl]-2,2,2-trifluoroethanamine
CID 175232836
3-(2,4-difluorophenyl)cyclopent-2-en-1-amine
CID 65174225
3-(2,4-difluorophenyl)cyclohex-2-en-1-ol
CID 65177210
3-(2,4-difluorophenyl)cyclohept-2-en-1-ol
CID 107383480
(2S)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide;(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide;2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide;methyl thiohypofluorite
CID 157143150
(2R)-5-(2,4-difluorophenyl)-2-ethyl-2-(2,2,2-trifluoroethyl)-3,4-dihydropyran
CID 153410094
6-(2,4-difluorophenyl)-2-methyl-1,2,3,4-tetrahydroquinoline
CID 81224165
[5-(2,4-difluorophenyl)-3-ethyl-2-methyl-3,4-dihydropyran-2-yl]methanol
CID 153410052

Frequently Asked Questions

What is the IUPAC name of (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran?
The IUPAC name of (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran (CID 153410075) is (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran.
What is the SMILES notation for (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran?
The canonical SMILES for (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran is Fc1ccc(C2=CO[C@@H](C(F)F)CC2)c(F)c1.
What is the InChIKey of (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran?
The InChIKey is FEUCAUDGGTXNNL-LLVKDONJSA-N. The full InChI is InChI=1S/C12H10F4O/c13-8-2-3-9(10(14)5-8)7-1-4-11(12(15)16)17-6-7/h2-3,5-6,11-12H,1,4H2/t11-/m1/s1.
What are the key properties of (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran?
(2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran has a molecular weight of 246.20 g/mol, XLogP of 3.75, 2 rotatable bonds, 0 hydrogen bond donors, and 1 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-2-(difluoromethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyran is sourced from PubChem (CID 153410075), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).