(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine

C14H18F3N — CID 155148305

IUPAC(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine
SMILESCC(C)N1CCC(F)(F)C[C@@H]1c1ccc(F)cc1
InChIInChI=1S/C14H18F3N/c1-10(2)18-8-7-14(16,17)9-13(18)11-3-5-12(15)6-4-11/h3-6,10,13H,7-9H2,1-2H3/t13-/m1/s1
InChIKeyUHTAVZQDOQSUJH-CYBMUJFWSA-N
MW257.30 g/mol
LogP4.01
Rot. Bonds2

About (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine

(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine (PubChem CID 155148305) has the molecular formula C14H18F3N and a molecular weight of 257.30 g/mol. Its IUPAC name is (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine.

Molecular Properties

Compound Name(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine
PubChem CID155148305
Molecular FormulaC14H18F3N
Molecular Weight257.30 g/mol
Exact Mass257.14
IUPAC Name(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine
SMILESCC(C)N1CCC(F)(F)C[C@@H]1c1ccc(F)cc1
InChIInChI=1S/C14H18F3N/c1-10(2)18-8-7-14(16,17)9-13(18)11-3-5-12(15)6-4-11/h3-6,10,13H,7-9H2,1-2H3/t13-/m1/s1
InChIKeyUHTAVZQDOQSUJH-CYBMUJFWSA-N
XLogP4.01
TPSA3.24 Ų
H-Bond Donors
H-Bond Acceptors1
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500257.30
LogP ≤ 54.01
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 101

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Related Compounds

1,4,4-trifluoro-2-(4-fluorophenyl)piperidine
CID 145285323
(2R)-2-(4-fluorophenyl)-1-propan-2-ylpiperidine
CID 124501109
(2R)-4-ethyl-2-(4-fluorophenyl)-1-propan-2-ylpiperazine
CID 140925009
(2R,4S)-2-(4-fluorophenyl)-1-propan-2-yl-4-(trifluoromethyl)piperidine
CID 140925003
(2S,4R)-2-(4-fluorophenyl)-N,1-di(propan-2-yl)piperidin-4-amine
CID 176681929
(3S)-3-(4-fluorophenyl)-1-propan-2-ylpyrrolidine
CID 166826823
4-(4-fluorophenyl)-2-methyl-8-propan-2-yl-2,8-diazaspiro[4.5]decan-1-one
CID 67986626
(3R,4S)-3-(4-fluorophenyl)-4-methyl-1-propan-2-ylpyrrolidine
CID 58601309
2-(4-cyclopropylphenyl)-1-propan-2-ylpyrrolidine
CID 167249235
2-phenyl-1-propan-2-yl-1,4-diazepane
CID 82242017
ethane;1-(4-fluorophenyl)-4-propan-2-ylpiperazine
CID 144656780
(2R)-2-(2,5-difluorophenyl)-1-propan-2-ylpyrrolidine
CID 166802320

Frequently Asked Questions

What is the IUPAC name of (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine?
The IUPAC name of (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine (CID 155148305) is (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine.
What is the SMILES notation for (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine?
The canonical SMILES for (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine is CC(C)N1CCC(F)(F)C[C@@H]1c1ccc(F)cc1.
What is the InChIKey of (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine?
The InChIKey is UHTAVZQDOQSUJH-CYBMUJFWSA-N. The full InChI is InChI=1S/C14H18F3N/c1-10(2)18-8-7-14(16,17)9-13(18)11-3-5-12(15)6-4-11/h3-6,10,13H,7-9H2,1-2H3/t13-/m1/s1.
What are the key properties of (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine?
(2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine has a molecular weight of 257.30 g/mol, XLogP of 4.01, 2 rotatable bonds, 0 hydrogen bond donors, and 1 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-4,4-difluoro-2-(4-fluorophenyl)-1-propan-2-ylpiperidine is sourced from PubChem (CID 155148305), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).