5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine

C10H12ClFN2Si — CID 156715435

IUPAC5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine
SMILESC[Si](C)(C)C#Cc1cc(Cl)c(F)nc1N
InChIInChI=1S/C10H12ClFN2Si/c1-15(2,3)5-4-7-6-8(11)9(12)14-10(7)13/h6H,1-3H3,(H2,13,14)
InChIKeyGDVBHRTUECSNGG-UHFFFAOYSA-N
MW242.76 g/mol
LogP2.69
Rot. Bonds

About 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine

5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine (PubChem CID 156715435) has the molecular formula C10H12ClFN2Si and a molecular weight of 242.76 g/mol. Its IUPAC name is 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine.

Molecular Properties

Compound Name5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine
PubChem CID156715435
Molecular FormulaC10H12ClFN2Si
Molecular Weight242.76 g/mol
Exact Mass242.04
IUPAC Name5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine
SMILESC[Si](C)(C)C#Cc1cc(Cl)c(F)nc1N
InChIInChI=1S/C10H12ClFN2Si/c1-15(2,3)5-4-7-6-8(11)9(12)14-10(7)13/h6H,1-3H3,(H2,13,14)
InChIKeyGDVBHRTUECSNGG-UHFFFAOYSA-N
XLogP2.69
TPSA38.91 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds
Heavy Atoms15
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500242.76
LogP ≤ 52.69
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

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Related Compounds

5,6-dimethyl-3-(2-trimethylsilylethynyl)pyridin-2-amine
CID 59747902
5-isocyano-6-methyl-3-(2-trimethylsilylethynyl)pyridin-2-amine
CID 123932620
2-[2,4-difluoro-5-(2-trimethylsilylethynyl)phenyl]ethynyl-trimethylsilane
CID 102134851
4-amino-2-chloro-5-(2-trimethylsilylethynyl)benzonitrile
CID 86222791
2-(2-chloro-5-fluoro-3-pyridinyl)ethynyl-trimethylsilane
CID 170905430
2-(3,6-dichloropyridazin-4-yl)ethynyl-trimethylsilane
CID 170916693
3-bromo-4-chloro-6-fluoro-2-(2-trimethylsilylethynyl)aniline
CID 171810662
5-bromo-3-ethynylpyridin-2-amine;5-bromo-3-(2-trimethylsilylethynyl)pyridin-2-amine
CID 160524655
tert-butyl-[[2,6-dichloro-3-fluoro-4-(2-trimethylsilylethynyl)phenyl]methoxy]-dimethylsilane
CID 162522855
2-fluoro-4-nitro-6-(2-trimethylsilylethynyl)aniline
CID 154776252
ethyl 4-amino-2-chloro-5-(2-trimethylsilylethynyl)benzoate
CID 58688773
2-(2-bromo-4-fluorophenyl)ethynyl-trimethylsilane
CID 168984861

Frequently Asked Questions

What is the IUPAC name of 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine?
The IUPAC name of 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine (CID 156715435) is 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine.
What is the SMILES notation for 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine?
The canonical SMILES for 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine is C[Si](C)(C)C#Cc1cc(Cl)c(F)nc1N.
What is the InChIKey of 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine?
The InChIKey is GDVBHRTUECSNGG-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H12ClFN2Si/c1-15(2,3)5-4-7-6-8(11)9(12)14-10(7)13/h6H,1-3H3,(H2,13,14).
What are the key properties of 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine?
5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine has a molecular weight of 242.76 g/mol, XLogP of 2.69, 0 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-6-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine is sourced from PubChem (CID 156715435), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).