N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide

C131H123F18N45O8 — CID 157124510

About N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide

N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide (PubChem CID 157124510) has the molecular formula C131H123F18N45O8 and a molecular weight of 2797.70 g/mol. Its IUPAC name is N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide.

Molecular Properties

• Compound Name: N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
• PubChem CID: 157124510
• Molecular Formula: C131H123F18N45O8
• Molecular Weight: 2797.70 g/mol
• Exact Mass: 2796.03
• IUPAC Name: N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
• SMILES: Cc1cc(Nc2cccc(C(F)(F)F)c2)cnc1C(=O)NNc1ncc(F)c(N2CCOCC2)n1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4nc(C)cc(-c5cccnc5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4nc(C)cc(NCCN5CCOCC5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4ncc(F)c(NCCN5CCOCC5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cncc(-c2nc(NNC(=O)c3ccc(Nc4cc(-n5cnc(C)c5)cc(C(F)(F)F)c4)cn3)ncc2F)c1
• InChI: InChI=1S/C28H31F3N10O2.C27H28F4N10O2.C27H21F4N9O.C27H22F3N9O.C22H21F4N7O2/c1-18-11-25(32-5-6-40-7-9-43-10-8-40)37-27(35-18)39-38-26(42)24-4-3-21(15-33-24)36-22-12-20(28(29,30)31)13-23(14-22)41-16-19(2)34-17-41;1-17-15-41(16-35-17)21-11-18(27(29,30)31)10-20(12-21)36-19-2-3-23(33-13-19)25(42)38-39-26-34-14-22(28)24(37-26)32-4-5-40-6-8-43-9-7-40;1-15-5-17(10-32-9-15)24-22(28)12-34-26(37-24)39-38-25(41)23-4-3-19(11-33-23)36-20-6-18(27(29,30)31)7-21(8-20)40-13-16(2)35-14-40;1-16-8-24(18-4-3-7-31-12-18)36-26(34-16)38-37-25(40)23-6-5-20(13-32-23)35-21-9-19(27(28,29)30)10-22(11-21)39-14-17(2)33-15-39;1-13-9-16(29-15-4-2-3-14(10-15)22(24,25)26)11-27-18(13)20(34)31-32-21-28-12-17(23)19(30-21)33-5-7-35-8-6-33/h3-4,11-17,36H,5-10H2,1-2H3,(H,38,42)(H2,32,35,37,39);2-3,10-16,36H,4-9H2,1H3,(H,38,42)(H2,32,34,37,39);3-14,36H,1-2H3,(H,38,41)(H,34,37,39);3-15,35H,1-2H3,(H,37,40)(H,34,36,38);2-4,9-12,29H,5-8H2,1H3,(H,31,34)(H,28,30,32)
• InChIKey: AIIYZXAXJZUSER-UHFFFAOYSA-N
• XLogP: 22.03
• TPSA: 617.68 Ų
• H-Bond Donors: 17
• H-Bond Acceptors: 48
• Rotatable Bonds: 40
• Heavy Atoms: 202
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2797.70
LogP ≤ 5	22.03
H-Bond Donors ≤ 5	17
H-Bond Acceptors ≤ 10	48

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide?

The IUPAC name of N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide (CID 157124510) is N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide.

What is the SMILES notation for N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide?

The canonical SMILES for N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide is Cc1cc(Nc2cccc(C(F)(F)F)c2)cnc1C(=O)NNc1ncc(F)c(N2CCOCC2)n1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4nc(C)cc(-c5cccnc5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4nc(C)cc(NCCN5CCOCC5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cn(-c2cc(Nc3ccc(C(=O)NNc4ncc(F)c(NCCN5CCOCC5)n4)nc3)cc(C(F)(F)F)c2)cn1.Cc1cncc(-c2nc(NNC(=O)c3ccc(Nc4cc(-n5cnc(C)c5)cc(C(F)(F)F)c4)cn3)ncc2F)c1.

What is the InChIKey of N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide?

The InChIKey is AIIYZXAXJZUSER-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H31F3N10O2.C27H28F4N10O2.C27H21F4N9O.C27H22F3N9O.C22H21F4N7O2/c1-18-11-25(32-5-6-40-7-9-43-10-8-40)37-27(35-18)39-38-26(42)24-4-3-21(15-33-24)36-22-12-20(28(29,30)31)13-23(14-22)41-16-19(2)34-17-41;1-17-15-41(16-35-17)21-11-18(27(29,30)31)10-20(12-21)36-19-2-3-23(33-13-19)25(42)38-39-26-34-14-22(28)24(37-26)32-4-5-40-6-8-43-9-7-40;1-15-5-17(10-32-9-15)24-22(28)12-34-26(37-24)39-38-25(41)23-4-3-19(11-33-23)36-20-6-18(27(29,30)31)7-21(8-20)40-13-16(2)35-14-40;1-16-8-24(18-4-3-7-31-12-18)36-26(34-16)38-37-25(40)23-6-5-20(13-32-23)35-21-9-19(27(28,29)30)10-22(11-21)39-14-17(2)33-15-39;1-13-9-16(29-15-4-2-3-14(10-15)22(24,25)26)11-27-18(13)20(34)31-32-21-28-12-17(23)19(30-21)33-5-7-35-8-6-33/h3-4,11-17,36H,5-10H2,1-2H3,(H,38,42)(H2,32,35,37,39);2-3,10-16,36H,4-9H2,1H3,(H,38,42)(H2,32,34,37,39);3-14,36H,1-2H3,(H,38,41)(H,34,37,39);3-15,35H,1-2H3,(H,37,40)(H,34,36,38);2-4,9-12,29H,5-8H2,1H3,(H,31,34)(H,28,30,32).

What are the key properties of N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide?

N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide has a molecular weight of 2797.70 g/mol, XLogP of 22.03, 40 rotatable bonds, 17 hydrogen bond donors, and 48 hydrogen bond acceptors.

Where does this data come from?

All data for N'-[5-fluoro-4-(5-methyl-3-pyridinyl)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]-5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-3-methyl-5-[3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-[4-methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide;5-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)anilino]-N'-(4-methyl-6-pyridin-3-ylpyrimidin-2-yl)pyridine-2-carbohydrazide is sourced from PubChem (CID 157124510), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).