6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine

C107H77Cl3F5N21O2 — CID 157156040

About 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine

6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine (PubChem CID 157156040) has the molecular formula C107H77Cl3F5N21O2 and a molecular weight of 1890.29 g/mol. Its IUPAC name is 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine.

Molecular Properties

• Compound Name: 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine
• PubChem CID: 157156040
• Molecular Formula: C107H77Cl3F5N21O2
• Molecular Weight: 1890.29 g/mol
• Exact Mass: 1887.56
• IUPAC Name: 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine
• SMILES: COc1cccc(-c2ncccc2-c2ccc3ncnc(N)c3c2)c1.Cc1cc(-c2ncccc2-c2ccc3ncnc(OC4CCN(c5ccncc5)CC4)c3c2)ccc1F.Nc1ncnc2ccc(-c3cccnc3-c3cc(Cl)c(F)cc3F)cc12.Nc1ncnc2ccc(-c3cccnc3-c3cc(Cl)ccc3F)cc12.Nc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12
• InChI: InChI=1S/C30H26FN5O.C20H16N4O.C19H11ClF2N4.2C19H12ClFN4/c1-20-17-22(4-6-27(20)31)29-25(3-2-12-33-29)21-5-7-28-26(18-21)30(35-19-34-28)37-24-10-15-36(16-11-24)23-8-13-32-14-9-23;1-25-15-5-2-4-14(10-15)19-16(6-3-9-22-19)13-7-8-18-17(11-13)20(21)24-12-23-18;20-14-7-12(15(21)8-16(14)22)18-11(2-1-5-24-18)10-3-4-17-13(6-10)19(23)26-9-25-17;20-12-4-5-16(21)14(9-12)18-13(2-1-7-23-18)11-3-6-17-15(8-11)19(22)25-10-24-17;20-15-9-12(3-5-16(15)21)18-13(2-1-7-23-18)11-4-6-17-14(8-11)19(22)25-10-24-17/h2-9,12-14,17-19,24H,10-11,15-16H2,1H3;2-12H,1H3,(H2,21,23,24);1-9H,(H2,23,25,26);2*1-10H,(H2,22,24,25)
• InChIKey: ALUXCPSBLUVLIS-UHFFFAOYSA-N
• XLogP: 24.54
• TPSA: 332.02 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 23
• Rotatable Bonds: 14
• Heavy Atoms: 138
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1890.29
LogP ≤ 5	24.54
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	23

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'halogenated_ring_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine?

The IUPAC name of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine (CID 157156040) is 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine.

What is the SMILES notation for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine?

The canonical SMILES for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine is COc1cccc(-c2ncccc2-c2ccc3ncnc(N)c3c2)c1.Cc1cc(-c2ncccc2-c2ccc3ncnc(OC4CCN(c5ccncc5)CC4)c3c2)ccc1F.Nc1ncnc2ccc(-c3cccnc3-c3cc(Cl)c(F)cc3F)cc12.Nc1ncnc2ccc(-c3cccnc3-c3cc(Cl)ccc3F)cc12.Nc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.

What is the InChIKey of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine?

The InChIKey is ALUXCPSBLUVLIS-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H26FN5O.C20H16N4O.C19H11ClF2N4.2C19H12ClFN4/c1-20-17-22(4-6-27(20)31)29-25(3-2-12-33-29)21-5-7-28-26(18-21)30(35-19-34-28)37-24-10-15-36(16-11-24)23-8-13-32-14-9-23;1-25-15-5-2-4-14(10-15)19-16(6-3-9-22-19)13-7-8-18-17(11-13)20(21)24-12-23-18;20-14-7-12(15(21)8-16(14)22)18-11(2-1-5-24-18)10-3-4-17-13(6-10)19(23)26-9-25-17;20-12-4-5-16(21)14(9-12)18-13(2-1-7-23-18)11-3-6-17-15(8-11)19(22)25-10-24-17;20-15-9-12(3-5-16(15)21)18-13(2-1-7-23-18)11-4-6-17-14(8-11)19(22)25-10-24-17/h2-9,12-14,17-19,24H,10-11,15-16H2,1H3;2-12H,1H3,(H2,21,23,24);1-9H,(H2,23,25,26);2*1-10H,(H2,22,24,25).

What are the key properties of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine?

6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine has a molecular weight of 1890.29 g/mol, XLogP of 24.54, 14 rotatable bonds, 4 hydrogen bond donors, and 23 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-(1-pyridin-4-ylpiperidin-4-yl)oxyquinazoline;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine is sourced from PubChem (CID 157156040), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).