(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide

C363H423Cl7F18N72O34 — CID 157253459

IUPAC(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide
SMILESCC(C)(C)n1c(NC(=O)C[C@](C)(O)c2ccccc2F)nc2ccc(Cl)nc21.CC(C)(O)CC(=O)Nc1nc2c(C(F)(F)F)ccnc2n1C1CCC1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1-c1ccc(OC(F)(F)F)cc1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1cc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C2(C)CCC2)cc1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cc(F)cc(F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)(F)F)c(Cl)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cccc(OC(F)(F)F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2n1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)c1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C(C)(C)C)c1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1)n2C1CCC1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1F)n2C1CCC1
InChIInChI=1S/3C22H25ClN4O2.2C22H26N4O2.C21H25ClN4O2.C21H23F3N4O3.C21H23FN4O2.C21H24N4O2.C20H20ClF3N4O2.C20H22ClFN4O2.C20H21F3N4O2.C20H22F2N4O2.C19H20F2N4O.C18H25ClN4O.C18H26N4O2.C18H26N4O.C16H19F3N4O2/c1-14-5-7-15(8-6-14)22(3,29)13-18(28)26-20-24-16-9-10-17(23)25-19(16)27(20)21(2)11-4-12-21;2*1-14-12-16-19(26-18(14)23)27(21(2)10-7-11-21)20(24-16)25-17(28)13-22(3,29)15-8-5-4-6-9-15;1-14-6-4-7-16(10-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-8-5-9-17;1-14-7-9-16(10-8-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-5-4-6-17;1-13-7-6-8-14(11-13)21(5,28)12-17(27)25-19-23-15-9-10-16(22)24-18(15)26(19)20(2,3)4;1-4-20(30,5-2)12-17(29)27-19-26-16-11-6-13(3)25-18(16)28(19)14-7-9-15(10-8-14)31-21(22,23)24;1-13-10-17-19(23-12-13)26(14-6-5-7-14)20(24-17)25-18(27)11-21(2,28)15-8-3-4-9-16(15)22;1-14-11-17-19(22-13-14)25(16-9-6-10-16)20(23-17)24-18(26)12-21(2,27)15-7-4-3-5-8-15;1-11-5-7-14-17(25-11)28(18(26-14)27-16(29)10-19(2,3)4)12-6-8-15(13(21)9-12)30-20(22,23)24;1-19(2,3)26-17-14(9-10-15(21)24-17)23-18(26)25-16(27)11-20(4,28)12-7-5-6-8-13(12)22;1-12-8-9-15-17(24-12)27(18(25-15)26-16(28)11-19(2,3)4)13-6-5-7-14(10-13)29-20(21,22)23;1-12-5-10-15-17(23-12)26(13-6-8-14(9-7-13)28-18(21)22)19(24-15)25-16(27)11-20(2,3)4;1-11-5-6-15-17(22-11)25(14-8-12(20)7-13(21)9-14)18(23-15)24-16(26)10-19(2,3)4;1-11-9-12-15(22-14(11)19)23(18(5)7-6-8-18)16(20-12)21-13(24)10-17(2,3)4;1-4-18(24,5-2)11-15(23)21-17-20-14-10-9-12(3)19-16(14)22(17)13-7-6-8-13;1-12-7-8-13-15(19-12)22(18(5)9-6-10-18)16(20-13)21-14(23)11-17(2,3)4;1-15(2,25)8-11(24)21-14-22-12-10(16(17,18)19)6-7-20-13(12)23(14)9-4-3-5-9/h5-10,29H,4,11-13H2,1-3H3,(H,24,26,28);2*4-6,8-9,12,29H,7,10-11,13H2,1-3H3,(H,24,25,28);4,6-7,10-11,13,17,28H,5,8-9,12H2,1-3H3,(H,24,25,27);7-11,13,17,28H,4-6,12H2,1-3H3,(H,24,25,27);6-11,28H,12H2,1-5H3,(H,23,25,27);6-11,30H,4-5,12H2,1-3H3,(H,26,27,29);3-4,8-10,12,14,28H,5-7,11H2,1-2H3,(H,24,25,27);3-5,7-8,11,13,16,27H,6,9-10,12H2,1-2H3,(H,23,24,26);5-9H,10H2,1-4H3,(H,26,27,29);5-10,28H,11H2,1-4H3,(H,23,25,27);5-10H,11H2,1-4H3,(H,25,26,28);5-10,18H,11H2,1-4H3,(H,24,25,27);5-9H,10H2,1-4H3,(H,23,24,26);9H,6-8,10H2,1-5H3,(H,20,21,24);9-10,13,24H,4-8,11H2,1-3H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);6-7,9,25H,3-5,8H2,1-2H3,(H,21,22,24)/t5*22-;21-;;2*21-;;20-;;;;;;;/m010000.00.0......./s1
InChIKeyAWPIQHYZYOJSPI-XZLQTUFXSA-N
MW6928.98 g/mol
LogP77.30
Rot. Bonds82

About (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide

(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide (PubChem CID 157253459) has the molecular formula C363H423Cl7F18N72O34 and a molecular weight of 6928.98 g/mol. Its IUPAC name is (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide.

Molecular Properties

Compound Name(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide
PubChem CID157253459
Molecular FormulaC363H423Cl7F18N72O34
Molecular Weight6928.98 g/mol
Exact Mass6921.11
IUPAC Name(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide
SMILESCC(C)(C)n1c(NC(=O)C[C@](C)(O)c2ccccc2F)nc2ccc(Cl)nc21.CC(C)(O)CC(=O)Nc1nc2c(C(F)(F)F)ccnc2n1C1CCC1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1-c1ccc(OC(F)(F)F)cc1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1cc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C2(C)CCC2)cc1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cc(F)cc(F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)(F)F)c(Cl)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cccc(OC(F)(F)F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2n1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)c1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C(C)(C)C)c1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1)n2C1CCC1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1F)n2C1CCC1
InChIInChI=1S/3C22H25ClN4O2.2C22H26N4O2.C21H25ClN4O2.C21H23F3N4O3.C21H23FN4O2.C21H24N4O2.C20H20ClF3N4O2.C20H22ClFN4O2.C20H21F3N4O2.C20H22F2N4O2.C19H20F2N4O.C18H25ClN4O.C18H26N4O2.C18H26N4O.C16H19F3N4O2/c1-14-5-7-15(8-6-14)22(3,29)13-18(28)26-20-24-16-9-10-17(23)25-19(16)27(20)21(2)11-4-12-21;2*1-14-12-16-19(26-18(14)23)27(21(2)10-7-11-21)20(24-16)25-17(28)13-22(3,29)15-8-5-4-6-9-15;1-14-6-4-7-16(10-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-8-5-9-17;1-14-7-9-16(10-8-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-5-4-6-17;1-13-7-6-8-14(11-13)21(5,28)12-17(27)25-19-23-15-9-10-16(22)24-18(15)26(19)20(2,3)4;1-4-20(30,5-2)12-17(29)27-19-26-16-11-6-13(3)25-18(16)28(19)14-7-9-15(10-8-14)31-21(22,23)24;1-13-10-17-19(23-12-13)26(14-6-5-7-14)20(24-17)25-18(27)11-21(2,28)15-8-3-4-9-16(15)22;1-14-11-17-19(22-13-14)25(16-9-6-10-16)20(23-17)24-18(26)12-21(2,27)15-7-4-3-5-8-15;1-11-5-7-14-17(25-11)28(18(26-14)27-16(29)10-19(2,3)4)12-6-8-15(13(21)9-12)30-20(22,23)24;1-19(2,3)26-17-14(9-10-15(21)24-17)23-18(26)25-16(27)11-20(4,28)12-7-5-6-8-13(12)22;1-12-8-9-15-17(24-12)27(18(25-15)26-16(28)11-19(2,3)4)13-6-5-7-14(10-13)29-20(21,22)23;1-12-5-10-15-17(23-12)26(13-6-8-14(9-7-13)28-18(21)22)19(24-15)25-16(27)11-20(2,3)4;1-11-5-6-15-17(22-11)25(14-8-12(20)7-13(21)9-14)18(23-15)24-16(26)10-19(2,3)4;1-11-9-12-15(22-14(11)19)23(18(5)7-6-8-18)16(20-12)21-13(24)10-17(2,3)4;1-4-18(24,5-2)11-15(23)21-17-20-14-10-9-12(3)19-16(14)22(17)13-7-6-8-13;1-12-7-8-13-15(19-12)22(18(5)9-6-10-18)16(20-13)21-14(23)11-17(2,3)4;1-15(2,25)8-11(24)21-14-22-12-10(16(17,18)19)6-7-20-13(12)23(14)9-4-3-5-9/h5-10,29H,4,11-13H2,1-3H3,(H,24,26,28);2*4-6,8-9,12,29H,7,10-11,13H2,1-3H3,(H,24,25,28);4,6-7,10-11,13,17,28H,5,8-9,12H2,1-3H3,(H,24,25,27);7-11,13,17,28H,4-6,12H2,1-3H3,(H,24,25,27);6-11,28H,12H2,1-5H3,(H,23,25,27);6-11,30H,4-5,12H2,1-3H3,(H,26,27,29);3-4,8-10,12,14,28H,5-7,11H2,1-2H3,(H,24,25,27);3-5,7-8,11,13,16,27H,6,9-10,12H2,1-2H3,(H,23,24,26);5-9H,10H2,1-4H3,(H,26,27,29);5-10,28H,11H2,1-4H3,(H,23,25,27);5-10H,11H2,1-4H3,(H,25,26,28);5-10,18H,11H2,1-4H3,(H,24,25,27);5-9H,10H2,1-4H3,(H,23,24,26);9H,6-8,10H2,1-5H3,(H,20,21,24);9-10,13,24H,4-8,11H2,1-3H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);6-7,9,25H,3-5,8H2,1-2H3,(H,21,22,24)/t5*22-;21-;;2*21-;;20-;;;;;;;/m010000.00.0......./s1
InChIKeyAWPIQHYZYOJSPI-XZLQTUFXSA-N
XLogP77.30
TPSA1356.26 Ų
H-Bond Donors30
H-Bond Acceptors88
Rotatable Bonds82
Heavy Atoms494
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5006928.98
LogP ≤ 577.30
H-Bond Donors ≤ 530
H-Bond Acceptors ≤ 1088

Analyze (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide?
The IUPAC name of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide (CID 157253459) is (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide.
What is the SMILES notation for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide?
The canonical SMILES for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide is CC(C)(C)n1c(NC(=O)C[C@](C)(O)c2ccccc2F)nc2ccc(Cl)nc21.CC(C)(O)CC(=O)Nc1nc2c(C(F)(F)F)ccnc2n1C1CCC1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1-c1ccc(OC(F)(F)F)cc1.CCC(O)(CC)CC(=O)Nc1nc2ccc(C)nc2n1C1CCC1.Cc1cc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C3(C)CCC3)c2nc1Cl.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)cc1.Cc1ccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C2(C)CCC2)cc1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cc(F)cc(F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)(F)F)c(Cl)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3cccc(OC(F)(F)F)c3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3(C)CCC3)c2n1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3cc(C)cnc3n2C2CCC2)c1.Cc1cccc([C@@](C)(O)CC(=O)Nc2nc3ccc(Cl)nc3n2C(C)(C)C)c1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1)n2C1CCC1.Cc1cnc2c(c1)nc(NC(=O)C[C@](C)(O)c1ccccc1F)n2C1CCC1.
What is the InChIKey of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide?
The InChIKey is AWPIQHYZYOJSPI-XZLQTUFXSA-N. The full InChI is InChI=1S/3C22H25ClN4O2.2C22H26N4O2.C21H25ClN4O2.C21H23F3N4O3.C21H23FN4O2.C21H24N4O2.C20H20ClF3N4O2.C20H22ClFN4O2.C20H21F3N4O2.C20H22F2N4O2.C19H20F2N4O.C18H25ClN4O.C18H26N4O2.C18H26N4O.C16H19F3N4O2/c1-14-5-7-15(8-6-14)22(3,29)13-18(28)26-20-24-16-9-10-17(23)25-19(16)27(20)21(2)11-4-12-21;2*1-14-12-16-19(26-18(14)23)27(21(2)10-7-11-21)20(24-16)25-17(28)13-22(3,29)15-8-5-4-6-9-15;1-14-6-4-7-16(10-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-8-5-9-17;1-14-7-9-16(10-8-14)22(3,28)12-19(27)25-21-24-18-11-15(2)13-23-20(18)26(21)17-5-4-6-17;1-13-7-6-8-14(11-13)21(5,28)12-17(27)25-19-23-15-9-10-16(22)24-18(15)26(19)20(2,3)4;1-4-20(30,5-2)12-17(29)27-19-26-16-11-6-13(3)25-18(16)28(19)14-7-9-15(10-8-14)31-21(22,23)24;1-13-10-17-19(23-12-13)26(14-6-5-7-14)20(24-17)25-18(27)11-21(2,28)15-8-3-4-9-16(15)22;1-14-11-17-19(22-13-14)25(16-9-6-10-16)20(23-17)24-18(26)12-21(2,27)15-7-4-3-5-8-15;1-11-5-7-14-17(25-11)28(18(26-14)27-16(29)10-19(2,3)4)12-6-8-15(13(21)9-12)30-20(22,23)24;1-19(2,3)26-17-14(9-10-15(21)24-17)23-18(26)25-16(27)11-20(4,28)12-7-5-6-8-13(12)22;1-12-8-9-15-17(24-12)27(18(25-15)26-16(28)11-19(2,3)4)13-6-5-7-14(10-13)29-20(21,22)23;1-12-5-10-15-17(23-12)26(13-6-8-14(9-7-13)28-18(21)22)19(24-15)25-16(27)11-20(2,3)4;1-11-5-6-15-17(22-11)25(14-8-12(20)7-13(21)9-14)18(23-15)24-16(26)10-19(2,3)4;1-11-9-12-15(22-14(11)19)23(18(5)7-6-8-18)16(20-12)21-13(24)10-17(2,3)4;1-4-18(24,5-2)11-15(23)21-17-20-14-10-9-12(3)19-16(14)22(17)13-7-6-8-13;1-12-7-8-13-15(19-12)22(18(5)9-6-10-18)16(20-13)21-14(23)11-17(2,3)4;1-15(2,25)8-11(24)21-14-22-12-10(16(17,18)19)6-7-20-13(12)23(14)9-4-3-5-9/h5-10,29H,4,11-13H2,1-3H3,(H,24,26,28);2*4-6,8-9,12,29H,7,10-11,13H2,1-3H3,(H,24,25,28);4,6-7,10-11,13,17,28H,5,8-9,12H2,1-3H3,(H,24,25,27);7-11,13,17,28H,4-6,12H2,1-3H3,(H,24,25,27);6-11,28H,12H2,1-5H3,(H,23,25,27);6-11,30H,4-5,12H2,1-3H3,(H,26,27,29);3-4,8-10,12,14,28H,5-7,11H2,1-2H3,(H,24,25,27);3-5,7-8,11,13,16,27H,6,9-10,12H2,1-2H3,(H,23,24,26);5-9H,10H2,1-4H3,(H,26,27,29);5-10,28H,11H2,1-4H3,(H,23,25,27);5-10H,11H2,1-4H3,(H,25,26,28);5-10,18H,11H2,1-4H3,(H,24,25,27);5-9H,10H2,1-4H3,(H,23,24,26);9H,6-8,10H2,1-5H3,(H,20,21,24);9-10,13,24H,4-8,11H2,1-3H3,(H,20,21,23);7-8H,6,9-11H2,1-5H3,(H,20,21,23);6-7,9,25H,3-5,8H2,1-2H3,(H,21,22,24)/t5*22-;21-;;2*21-;;20-;;;;;;;/m010000.00.0......./s1.
What are the key properties of (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide?
(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide has a molecular weight of 6928.98 g/mol, XLogP of 77.30, 82 rotatable bonds, 30 hydrogen bond donors, and 88 hydrogen bond acceptors.
Where does this data come from?
All data for (3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-chloroimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-[5-chloro-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-(4-methylphenyl)butanamide;N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;(3S)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-6-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-ethyl-3-hydroxypentanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-(2-fluorophenyl)-3-hydroxybutanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(3-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(4-methylphenyl)butanamide;(3S)-N-(3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide;N-[3-[4-(difluoromethoxy)phenyl]-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[3-(3,5-difluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;3,3-dimethyl-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[3-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-ethyl-3-hydroxy-N-[5-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]pentanamide is sourced from PubChem (CID 157253459), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).