6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol

C122H148ClN19O13S — CID 157276210

About 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol

6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol (PubChem CID 157276210) has the molecular formula C122H148ClN19O13S and a molecular weight of 2156.17 g/mol. Its IUPAC name is 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol.

Molecular Properties

• Compound Name: 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol
• PubChem CID: 157276210
• Molecular Formula: C122H148ClN19O13S
• Molecular Weight: 2156.17 g/mol
• Exact Mass: 2154.09
• IUPAC Name: 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol
• SMILES: CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)O)cc3n2)cs1.COc1ccc2c(OC(C)(C)C)cc(-c3ccn(C(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3cncc(C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3nccc(C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-n3ccc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)C)cc(-c3cccc(NC(C)C)n3)nc2c1Cl
• InChI: InChI=1S/C23H31N3O3S.C21H24ClN3O2.C20H26N4O2.C20H25N3O2.2C19H21N3O2/c1-14(2)24-21-26-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)25-18)28-13-23(6,7)27;1-12(2)23-19-8-6-7-15(24-19)16-11-18(27-13(3)4)14-9-10-17(26-5)20(22)21(14)25-16;1-13(2)21-18-9-10-24(23-18)19-12-17(26-20(3,4)5)15-8-7-14(25-6)11-16(15)22-19;1-13(2)23-10-9-16(22-23)18-12-19(25-20(3,4)5)15-8-7-14(24-6)11-17(15)21-18;1-12-10-20-11-17(21-12)16-9-18(24-19(2,3)4)14-7-6-13(23-5)8-15(14)22-16;1-12-8-9-20-18(21-12)16-11-17(24-19(2,3)4)14-7-6-13(23-5)10-15(14)22-16/h8-12,14,27H,13H2,1-7H3,(H,24,26);6-13H,1-5H3,(H,23,24);7-13H,1-6H3,(H,21,23);7-13H,1-6H3;2*6-11H,1-5H3
• InChIKey: AZDDCZVMPAKDOZ-UHFFFAOYSA-N
• XLogP: 28.74
• TPSA: 357.40 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 33
• Rotatable Bonds: 28
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2156.17
LogP ≤ 5	28.74
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The IUPAC name of 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol (CID 157276210) is 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol.

What is the SMILES notation for 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The canonical SMILES for 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol is CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)O)cc3n2)cs1.COc1ccc2c(OC(C)(C)C)cc(-c3ccn(C(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3cncc(C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3nccc(C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-n3ccc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)C)cc(-c3cccc(NC(C)C)n3)nc2c1Cl.

What is the InChIKey of 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The InChIKey is AZDDCZVMPAKDOZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H31N3O3S.C21H24ClN3O2.C20H26N4O2.C20H25N3O2.2C19H21N3O2/c1-14(2)24-21-26-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)25-18)28-13-23(6,7)27;1-12(2)23-19-8-6-7-15(24-19)16-11-18(27-13(3)4)14-9-10-17(26-5)20(22)21(14)25-16;1-13(2)21-18-9-10-24(23-18)19-12-17(26-20(3,4)5)15-8-7-14(25-6)11-16(15)22-19;1-13(2)23-10-9-16(22-23)18-12-19(25-20(3,4)5)15-8-7-14(24-6)11-17(15)21-18;1-12-10-20-11-17(21-12)16-9-18(24-19(2,3)4)14-7-6-13(23-5)8-15(14)22-16;1-12-8-9-20-18(21-12)16-11-17(24-19(2,3)4)14-7-6-13(23-5)10-15(14)22-16/h8-12,14,27H,13H2,1-7H3,(H,24,26);6-13H,1-5H3,(H,23,24);7-13H,1-6H3,(H,21,23);7-13H,1-6H3;2*6-11H,1-5H3.

What are the key properties of 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol has a molecular weight of 2156.17 g/mol, XLogP of 28.74, 28 rotatable bonds, 4 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(8-chloro-7-methoxy-4-propan-2-yloxyquinolin-2-yl)-N-propan-2-ylpyridin-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(1-propan-2-ylpyrazol-3-yl)quinoline;1-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-ylpyrazol-3-amine;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol is sourced from PubChem (CID 157276210), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).