N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide

C117H145F3N26O12 — CID 157398176

About N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide

N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide (PubChem CID 157398176) has the molecular formula C117H145F3N26O12 and a molecular weight of 2164.61 g/mol. Its IUPAC name is N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide.

Molecular Properties

• Compound Name: N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide
• PubChem CID: 157398176
• Molecular Formula: C117H145F3N26O12
• Molecular Weight: 2164.61 g/mol
• Exact Mass: 2163.15
• IUPAC Name: N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide
• SMILES: CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(C3(C)CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)C3CC3)n(C3(C)CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)C3CC3)n(C3CCC3)c2n1.Cc1nc2c(cc1C#N)nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1nc2c(cc1C#N)nc(NC(=O)C[C@](C)(O)c1ccccc1)n2C1CCC1
• InChI: InChI=1S/C22H23N5O2.C21H23F3N4O4.C19H26N4O2.C19H26N4O.C18H23N5O.C18H24N4O2/c1-14-15(13-23)11-18-20(24-14)27(17-9-6-10-17)21(25-18)26-19(28)12-22(2,29)16-7-4-3-5-8-16;1-19(2,30)11-16(29)27-18-25-14-9-10-15(20(3,4)31)26-17(14)28(18)12-5-7-13(8-6-12)32-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-13-6-7-14-16(20-13)23(19(3)10-5-11-19)17(21-14)22-15(24)12-18(2)8-4-9-18;1-11-12(10-19)8-14-16(20-11)23(13-6-5-7-13)17(21-14)22-15(24)9-18(2,3)4;1-11-6-9-14-16(19-11)22(13-4-3-5-13)17(20-14)21-15(23)10-18(2,24)12-7-8-12/h3-5,7-8,11,17,29H,6,9-10,12H2,1-2H3,(H,25,26,28);5-10,30-31H,11H2,1-4H3,(H,25,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);6-7H,4-5,8-12H2,1-3H3,(H,21,22,24);8,13H,5-7,9H2,1-4H3,(H,21,22,24);6,9,12-13,24H,3-5,7-8,10H2,1-2H3,(H,20,21,23)/t22-;;19-;;;18-/m0.0..0/s1
• InChIKey: BMVCMSFQBKNGSD-ISBQKIKTSA-N
• XLogP: 21.17
• TPSA: 516.82 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 32
• Rotatable Bonds: 28
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2164.61
LogP ≤ 5	21.17
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide?

The IUPAC name of N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide (CID 157398176) is N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide.

What is the SMILES notation for N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide?

The canonical SMILES for N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide is CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.Cc1ccc2nc(NC(=O)CC3(C)CCC3)n(C3(C)CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)C3CC3)n(C3(C)CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)C3CC3)n(C3CCC3)c2n1.Cc1nc2c(cc1C#N)nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1nc2c(cc1C#N)nc(NC(=O)C[C@](C)(O)c1ccccc1)n2C1CCC1.

What is the InChIKey of N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide?

The InChIKey is BMVCMSFQBKNGSD-ISBQKIKTSA-N. The full InChI is InChI=1S/C22H23N5O2.C21H23F3N4O4.C19H26N4O2.C19H26N4O.C18H23N5O.C18H24N4O2/c1-14-15(13-23)11-18-20(24-14)27(17-9-6-10-17)21(25-18)26-19(28)12-22(2,29)16-7-4-3-5-8-16;1-19(2,30)11-16(29)27-18-25-14-9-10-15(20(3,4)31)26-17(14)28(18)12-5-7-13(8-6-12)32-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-13-6-7-14-16(20-13)23(19(3)10-5-11-19)17(21-14)22-15(24)12-18(2)8-4-9-18;1-11-12(10-19)8-14-16(20-11)23(13-6-5-7-13)17(21-14)22-15(24)9-18(2,3)4;1-11-6-9-14-16(19-11)22(13-4-3-5-13)17(20-14)21-15(23)10-18(2,24)12-7-8-12/h3-5,7-8,11,17,29H,6,9-10,12H2,1-2H3,(H,25,26,28);5-10,30-31H,11H2,1-4H3,(H,25,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);6-7H,4-5,8-12H2,1-3H3,(H,21,22,24);8,13H,5-7,9H2,1-4H3,(H,21,22,24);6,9,12-13,24H,3-5,7-8,10H2,1-2H3,(H,20,21,23)/t22-;;19-;;;18-/m0.0..0/s1.

What are the key properties of N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide?

N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide has a molecular weight of 2164.61 g/mol, XLogP of 21.17, 28 rotatable bonds, 11 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3S)-N-(6-cyano-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3S)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;2-(1-methylcyclobutyl)-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]acetamide is sourced from PubChem (CID 157398176), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).