(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide

C125H153F9N24O15 — CID 158188992

About (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide

(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide (PubChem CID 158188992) has the molecular formula C125H153F9N24O15 and a molecular weight of 2402.73 g/mol. Its IUPAC name is (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide.

Molecular Properties

• Compound Name: (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide
• PubChem CID: 158188992
• Molecular Formula: C125H153F9N24O15
• Molecular Weight: 2402.73 g/mol
• Exact Mass: 2401.18
• IUPAC Name: (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide
• SMILES: CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC1(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2-c2ccc(OC(F)(F)F)cc2)CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(C)(C)C)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OCC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C3(C)CCC3)c2n1
• InChI: InChI=1S/C23H25F3N4O3.C23H30N4O2.C21H23F3N4O4.C21H23F3N4O2.C19H26N4O2.C18H26N4O2/c1-21(2,32)17-10-9-16-19(28-17)30(14-5-7-15(8-6-14)33-23(24,25)26)20(27-16)29-18(31)13-22(3)11-4-12-22;1-15-8-13-18-20(24-15)27(21(25-18)26-19(28)14-22(2,3)4)16-9-11-17(12-10-16)29-23(5,6)7;1-19(2,30)11-16(29)27-18-25-14-9-10-15(20(3,4)31)26-17(14)28(18)12-5-7-13(8-6-12)32-21(22,23)24;1-13-5-10-16-18(25-13)28(19(26-16)27-17(29)11-20(2,3)4)14-6-8-15(9-7-14)30-12-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-11-6-9-13-15(19-11)22(17(2,3)4)16(20-13)21-14(23)10-18(5,24)12-7-8-12/h5-10,32H,4,11-13H2,1-3H3,(H,27,29,31);8-13H,14H2,1-7H3,(H,25,26,28);5-10,30-31H,11H2,1-4H3,(H,25,27,29);5-10H,11-12H2,1-4H3,(H,26,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);6,9,12,24H,7-8,10H2,1-5H3,(H,20,21,23)/t;;;;19-;18-/m....11/s1
• InChIKey: FZMUYLZWTYHQCB-IGVRPKFNSA-N
• XLogP: 25.15
• TPSA: 496.93 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 33
• Rotatable Bonds: 30
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2402.73
LogP ≤ 5	25.15
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide?

The IUPAC name of (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide (CID 158188992) is (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide.

What is the SMILES notation for (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide?

The canonical SMILES for (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide is CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC1(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2-c2ccc(OC(F)(F)F)cc2)CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OC(C)(C)C)cc3)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(-c3ccc(OCC(F)(F)F)cc3)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@@](C)(O)C3CC3)n(C3(C)CCC3)c2n1.

What is the InChIKey of (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide?

The InChIKey is FZMUYLZWTYHQCB-IGVRPKFNSA-N. The full InChI is InChI=1S/C23H25F3N4O3.C23H30N4O2.C21H23F3N4O4.C21H23F3N4O2.C19H26N4O2.C18H26N4O2/c1-21(2,32)17-10-9-16-19(28-17)30(14-5-7-15(8-6-14)33-23(24,25)26)20(27-16)29-18(31)13-22(3)11-4-12-22;1-15-8-13-18-20(24-15)27(21(25-18)26-19(28)14-22(2,3)4)16-9-11-17(12-10-16)29-23(5,6)7;1-19(2,30)11-16(29)27-18-25-14-9-10-15(20(3,4)31)26-17(14)28(18)12-5-7-13(8-6-12)32-21(22,23)24;1-13-5-10-16-18(25-13)28(19(26-16)27-17(29)11-20(2,3)4)14-6-8-15(9-7-14)30-12-21(22,23)24;1-12-5-8-14-16(20-12)23(18(2)9-4-10-18)17(21-14)22-15(24)11-19(3,25)13-6-7-13;1-11-6-9-13-15(19-11)22(17(2,3)4)16(20-13)21-14(23)10-18(5,24)12-7-8-12/h5-10,32H,4,11-13H2,1-3H3,(H,27,29,31);8-13H,14H2,1-7H3,(H,25,26,28);5-10,30-31H,11H2,1-4H3,(H,25,27,29);5-10H,11-12H2,1-4H3,(H,26,27,29);5,8,13,25H,4,6-7,9-11H2,1-3H3,(H,21,22,24);6,9,12,24H,7-8,10H2,1-5H3,(H,20,21,23)/t;;;;19-;18-/m....11/s1.

What are the key properties of (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide?

(3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide has a molecular weight of 2402.73 g/mol, XLogP of 25.15, 30 rotatable bonds, 11 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for (3R)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-cyclopropyl-3-hydroxybutanamide;(3R)-3-cyclopropyl-3-hydroxy-N-[5-methyl-3-(1-methylcyclobutyl)imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3,3-dimethyl-N-[5-methyl-3-[4-(2,2,2-trifluoroethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]butanamide;3-hydroxy-N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3-methylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-2-(1-methylcyclobutyl)acetamide is sourced from PubChem (CID 158188992), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).