N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide

C187H156Cl8F17N39O18 — CID 157406034

IUPACN-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
SMILESCC(C)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3ccn[nH]3)c21.CC1(F)CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.CC1CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)cn1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C4CC4)c23)cn1.C[C@@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.C[C@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)c1
InChIInChI=1S/C24H19ClF3N5O2.3C24H20ClF2N5O2.C24H21ClF2N4O2.C23H18ClF2N5O3.C23H20ClF2N5O3.C21H18ClF2N5O2/c1-23(26)8-17(9-23)33-13-31-20-7-14(6-19(21(20)33)15-10-29-12-30-11-15)22(34)32-16-2-4-18(5-3-16)35-24(25,27)28;1-14-6-18(7-14)32-13-30-21-9-15(8-20(22(21)32)16-10-28-12-29-11-16)23(33)31-17-2-4-19(5-3-17)34-24(25,26)27;2*1-14(15-2-3-15)32-13-30-21-9-16(8-20(22(21)32)17-10-28-12-29-11-17)23(33)31-18-4-6-19(7-5-18)34-24(25,26)27;1-14(2)31-13-29-21-10-16(9-20(22(21)31)17-8-15(3)11-28-12-17)23(32)30-18-4-6-19(7-5-18)33-24(25,26)27;1-33-22-27-10-14(11-28-22)18-8-13(9-19-20(18)31(12-29-19)16-4-5-16)21(32)30-15-2-6-17(7-3-15)34-23(24,25)26;1-13(2)31-12-29-19-9-14(8-18(20(19)31)15-10-27-22(33-3)28-11-15)21(32)30-16-4-6-17(7-5-16)34-23(24,25)26;1-12(2)29-11-25-18-10-13(9-16(19(18)29)17-7-8-26-28-17)20(30)27-14-3-5-15(6-4-14)31-21(22,23)24/h2-7,10-13,17H,8-9H2,1H3,(H,32,34);2-5,8-14,18H,6-7H2,1H3,(H,31,33);2*4-15H,2-3H2,1H3,(H,31,33);4-14H,1-3H3,(H,30,32);2-3,6-12,16H,4-5H2,1H3,(H,30,32);4-13H,1-3H3,(H,30,32);3-12H,1-2H3,(H,26,28)(H,27,30)/t;;2*14-;;;;/m..10..../s1
InChIKeyBNSMEXKASNBJJD-KVXGNQICSA-N
MW3844.15 g/mol
LogP46.23
Rot. Bonds52

About N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide (PubChem CID 157406034) has the molecular formula C187H156Cl8F17N39O18 and a molecular weight of 3844.15 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide.

Molecular Properties

Compound NameN-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
PubChem CID157406034
Molecular FormulaC187H156Cl8F17N39O18
Molecular Weight3844.15 g/mol
Exact Mass3837.97
IUPAC NameN-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
SMILESCC(C)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3ccn[nH]3)c21.CC1(F)CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.CC1CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)cn1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C4CC4)c23)cn1.C[C@@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.C[C@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)c1
InChIInChI=1S/C24H19ClF3N5O2.3C24H20ClF2N5O2.C24H21ClF2N4O2.C23H18ClF2N5O3.C23H20ClF2N5O3.C21H18ClF2N5O2/c1-23(26)8-17(9-23)33-13-31-20-7-14(6-19(21(20)33)15-10-29-12-30-11-15)22(34)32-16-2-4-18(5-3-16)35-24(25,27)28;1-14-6-18(7-14)32-13-30-21-9-15(8-20(22(21)32)16-10-28-12-29-11-16)23(33)31-17-2-4-19(5-3-17)34-24(25,26)27;2*1-14(15-2-3-15)32-13-30-21-9-16(8-20(22(21)32)17-10-28-12-29-11-17)23(33)31-18-4-6-19(7-5-18)34-24(25,26)27;1-14(2)31-13-29-21-10-16(9-20(22(21)31)17-8-15(3)11-28-12-17)23(32)30-18-4-6-19(7-5-18)33-24(25,26)27;1-33-22-27-10-14(11-28-22)18-8-13(9-19-20(18)31(12-29-19)16-4-5-16)21(32)30-15-2-6-17(7-3-15)34-23(24,25)26;1-13(2)31-12-29-19-9-14(8-18(20(19)31)15-10-27-22(33-3)28-11-15)21(32)30-16-4-6-17(7-5-16)34-23(24,25)26;1-12(2)29-11-25-18-10-13(9-16(19(18)29)17-7-8-26-28-17)20(30)27-14-3-5-15(6-4-14)31-21(22,23)24/h2-7,10-13,17H,8-9H2,1H3,(H,32,34);2-5,8-14,18H,6-7H2,1H3,(H,31,33);2*4-15H,2-3H2,1H3,(H,31,33);4-14H,1-3H3,(H,30,32);2-3,6-12,16H,4-5H2,1H3,(H,30,32);4-13H,1-3H3,(H,30,32);3-12H,1-2H3,(H,26,28)(H,27,30)/t;;2*14-;;;;/m..10..../s1
InChIKeyBNSMEXKASNBJJD-KVXGNQICSA-N
XLogP46.23
TPSA663.91 Ų
H-Bond Donors9
H-Bond Acceptors48
Rotatable Bonds52
Heavy Atoms269
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003844.15
LogP ≤ 546.23
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1048

Analyze N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide
CID 146508269
N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide
CID 146507824
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(2S)-3-fluorobutan-2-yl]-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
CID 161448598
N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-pyridin-3-ylbenzimidazole-5-carboxamide
CID 158452875
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(2S)-1-methoxypropan-2-yl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide
CID 146507803
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(2R)-pent-4-yn-2-yl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide
CID 161448596
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(2R)-1-cyanopropan-2-yl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide
CID 146509062
N-[4-[chloro(difluoro)methoxy]phenyl]-3-methyl-1-propan-2-yl-7-(1H-pyrazol-5-yl)-2,3-dihydroindole-5-carboxamide
CID 156789561
N-[4-[chloro(difluoro)methoxy]phenyl]-2,3-dihydroxy-4-propan-2-yl-5-(1H-pyrazol-5-yl)-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]indole-7-carboxamide
CID 165163963
N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-2-(difluoromethyl)-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
CID 146507912
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[1-(hydroxymethyl)cyclopropyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide
CID 146508270
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(2R)-1-hydroxypropan-2-yl]-2-methoxy-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide
CID 146507867

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide?
The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide (CID 157406034) is N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide.
What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide?
The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide is CC(C)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3ccn[nH]3)c21.CC1(F)CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.CC1CC(n2cnc3cc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc(-c4cncnc4)c32)C1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)cn1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C4CC4)c23)cn1.C[C@@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.C[C@H](C1CC1)n1cnc2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc(-c3cncnc3)c21.Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3ncn(C(C)C)c23)c1.
What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide?
The InChIKey is BNSMEXKASNBJJD-KVXGNQICSA-N. The full InChI is InChI=1S/C24H19ClF3N5O2.3C24H20ClF2N5O2.C24H21ClF2N4O2.C23H18ClF2N5O3.C23H20ClF2N5O3.C21H18ClF2N5O2/c1-23(26)8-17(9-23)33-13-31-20-7-14(6-19(21(20)33)15-10-29-12-30-11-15)22(34)32-16-2-4-18(5-3-16)35-24(25,27)28;1-14-6-18(7-14)32-13-30-21-9-15(8-20(22(21)32)16-10-28-12-29-11-16)23(33)31-17-2-4-19(5-3-17)34-24(25,26)27;2*1-14(15-2-3-15)32-13-30-21-9-16(8-20(22(21)32)17-10-28-12-29-11-17)23(33)31-18-4-6-19(7-5-18)34-24(25,26)27;1-14(2)31-13-29-21-10-16(9-20(22(21)31)17-8-15(3)11-28-12-17)23(32)30-18-4-6-19(7-5-18)33-24(25,26)27;1-33-22-27-10-14(11-28-22)18-8-13(9-19-20(18)31(12-29-19)16-4-5-16)21(32)30-15-2-6-17(7-3-15)34-23(24,25)26;1-13(2)31-12-29-19-9-14(8-18(20(19)31)15-10-27-22(33-3)28-11-15)21(32)30-16-4-6-17(7-5-16)34-23(24,25)26;1-12(2)29-11-25-18-10-13(9-16(19(18)29)17-7-8-26-28-17)20(30)27-14-3-5-15(6-4-14)31-21(22,23)24/h2-7,10-13,17H,8-9H2,1H3,(H,32,34);2-5,8-14,18H,6-7H2,1H3,(H,31,33);2*4-15H,2-3H2,1H3,(H,31,33);4-14H,1-3H3,(H,30,32);2-3,6-12,16H,4-5H2,1H3,(H,30,32);4-13H,1-3H3,(H,30,32);3-12H,1-2H3,(H,26,28)(H,27,30)/t;;2*14-;;;;/m..10..../s1.
What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide?
N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide has a molecular weight of 3844.15 g/mol, XLogP of 46.23, 52 rotatable bonds, 9 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1S)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-[(1R)-1-cyclopropylethyl]-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-cyclopropyl-7-(2-methoxypyrimidin-5-yl)benzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-fluoro-3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(2-methoxypyrimidin-5-yl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-(3-methylcyclobutyl)-7-pyrimidin-5-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-7-(5-methyl-3-pyridinyl)-1-propan-2-ylbenzimidazole-5-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-1-propan-2-yl-7-(1H-pyrazol-5-yl)benzimidazole-5-carboxamide is sourced from PubChem (CID 157406034), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).