2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine

C64H56Cl8F2N14O5S2 — CID 157465594

About 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine

2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine (PubChem CID 157465594) has the molecular formula C64H56Cl8F2N14O5S2 and a molecular weight of 1487.00 g/mol. Its IUPAC name is 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine.

Molecular Properties

• Compound Name: 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine
• PubChem CID: 157465594
• Molecular Formula: C64H56Cl8F2N14O5S2
• Molecular Weight: 1487.00 g/mol
• Exact Mass: 1482.15
• IUPAC Name: 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine
• SMILES: C=C(NC1CC1)c1cc2c(-c3c(Cl)cc(Cl)c4c3CCO4)nc(N)nc2s1.CC(F)(F)CNC(=O)c1cc2c(-c3c(Cl)cc(Cl)c4c3CCO4)nc(N)nc2s1.Cc1cc(-c2c(Cl)cc(Cl)c3c2CCO3)nc(N)n1.Cc1cc(-c2cc(OC(C)C)c(Cl)cc2Cl)nc(N)n1
• InChI: InChI=1S/C19H16Cl2N4OS.C18H14Cl2F2N4O2S.C14H15Cl2N3O.C13H11Cl2N3O/c1-8(23-9-2-3-9)14-6-11-16(24-19(22)25-18(11)27-14)15-10-4-5-26-17(10)13(21)7-12(15)20;1-18(21,22)6-24-15(27)11-4-8-13(25-17(23)26-16(8)29-11)12-7-2-3-28-14(7)10(20)5-9(12)19;1-7(2)20-13-5-9(10(15)6-11(13)16)12-4-8(3)18-14(17)19-12;1-6-4-10(18-13(16)17-6)11-7-2-3-19-12(7)9(15)5-8(11)14/h6-7,9,23H,1-5H2,(H2,22,24,25);4-5H,2-3,6H2,1H3,(H,24,27)(H2,23,25,26);4-7H,1-3H3,(H2,17,18,19);4-5H,2-3H2,1H3,(H2,16,17,18)
• InChIKey: BUKZGPZMMUGMRW-UHFFFAOYSA-N
• XLogP: 16.88
• TPSA: 285.25 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 20
• Rotatable Bonds: 12
• Heavy Atoms: 95
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1487.00
LogP ≤ 5	16.88
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine?

The IUPAC name of 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine (CID 157465594) is 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine.

What is the SMILES notation for 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine?

The canonical SMILES for 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine is C=C(NC1CC1)c1cc2c(-c3c(Cl)cc(Cl)c4c3CCO4)nc(N)nc2s1.CC(F)(F)CNC(=O)c1cc2c(-c3c(Cl)cc(Cl)c4c3CCO4)nc(N)nc2s1.Cc1cc(-c2c(Cl)cc(Cl)c3c2CCO3)nc(N)n1.Cc1cc(-c2cc(OC(C)C)c(Cl)cc2Cl)nc(N)n1.

What is the InChIKey of 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine?

The InChIKey is BUKZGPZMMUGMRW-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16Cl2N4OS.C18H14Cl2F2N4O2S.C14H15Cl2N3O.C13H11Cl2N3O/c1-8(23-9-2-3-9)14-6-11-16(24-19(22)25-18(11)27-14)15-10-4-5-26-17(10)13(21)7-12(15)20;1-18(21,22)6-24-15(27)11-4-8-13(25-17(23)26-16(8)29-11)12-7-2-3-28-14(7)10(20)5-9(12)19;1-7(2)20-13-5-9(10(15)6-11(13)16)12-4-8(3)18-14(17)19-12;1-6-4-10(18-13(16)17-6)11-7-2-3-19-12(7)9(15)5-8(11)14/h6-7,9,23H,1-5H2,(H2,22,24,25);4-5H,2-3,6H2,1H3,(H,24,27)(H2,23,25,26);4-7H,1-3H3,(H2,17,18,19);4-5H,2-3H2,1H3,(H2,16,17,18).

What are the key properties of 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine?

2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine has a molecular weight of 1487.00 g/mol, XLogP of 16.88, 12 rotatable bonds, 6 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-N-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine-6-carboxamide;6-[1-(cyclopropylamino)ethenyl]-4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)thieno[2,3-d]pyrimidin-2-amine;4-(5,7-dichloro-2,3-dihydro-1-benzofuran-4-yl)-6-methylpyrimidin-2-amine;4-(2,4-dichloro-5-propan-2-yloxyphenyl)-6-methylpyrimidin-2-amine is sourced from PubChem (CID 157465594), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).