2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C97H119Cl5N42O7 — CID 158002061

IUPAC2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCN(C)CCN1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN1CCN(c2cc(N)ncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COC1(CN(C)C)CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COCC1CN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CCN1C.Nc1nn2cc(Cl)cnc2c1C(=O)Nc1cnccc1N1CCN(C2CCC2)CC1
InChIInChI=1S/C21H27ClN8O2.C20H26ClN9O.C20H23ClN8O.C19H23ClN8O2.C17H20ClN9O/c1-28(2)13-21(32-3)5-8-29(9-6-21)16-4-7-24-11-15(16)26-20(31)17-18(23)27-30-12-14(22)10-25-19(17)30;1-27(2)5-6-28-7-9-29(10-8-28)16-3-4-23-12-15(16)25-20(31)17-18(22)26-30-13-14(21)11-24-19(17)30;21-13-10-24-19-17(18(22)26-29(19)12-13)20(30)25-15-11-23-5-4-16(15)28-8-6-27(7-9-28)14-2-1-3-14;1-26-5-6-27(10-13(26)11-30-2)15-3-4-22-8-14(15)24-19(29)16-17(21)25-28-9-12(20)7-23-18(16)28;1-25-2-4-26(5-3-25)12-6-13(19)21-8-11(12)23-17(28)14-15(20)24-27-9-10(18)7-22-16(14)27/h4,7,10-12H,5-6,8-9,13H2,1-3H3,(H2,23,27)(H,26,31);3-4,11-13H,5-10H2,1-2H3,(H2,22,26)(H,25,31);4-5,10-12,14H,1-3,6-9H2,(H2,22,26)(H,25,30);3-4,7-9,13H,5-6,10-11H2,1-2H3,(H2,21,25)(H,24,29);6-9H,2-5H2,1H3,(H2,19,21)(H2,20,24)(H,23,28)
InChIKeyFDVUYCPERFLJHS-UHFFFAOYSA-N
MW2162.57 g/mol
LogP8.07
Rot. Bonds24

About 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 158002061) has the molecular formula C97H119Cl5N42O7 and a molecular weight of 2162.57 g/mol. Its IUPAC name is 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID158002061
Molecular FormulaC97H119Cl5N42O7
Molecular Weight2162.57 g/mol
Exact Mass2158.87
IUPAC Name2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCN(C)CCN1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN1CCN(c2cc(N)ncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COC1(CN(C)C)CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COCC1CN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CCN1C.Nc1nn2cc(Cl)cnc2c1C(=O)Nc1cnccc1N1CCN(C2CCC2)CC1
InChIInChI=1S/C21H27ClN8O2.C20H26ClN9O.C20H23ClN8O.C19H23ClN8O2.C17H20ClN9O/c1-28(2)13-21(32-3)5-8-29(9-6-21)16-4-7-24-11-15(16)26-20(31)17-18(23)27-30-12-14(22)10-25-19(17)30;1-27(2)5-6-28-7-9-29(10-8-28)16-3-4-23-12-15(16)25-20(31)17-18(22)26-30-13-14(21)11-24-19(17)30;21-13-10-24-19-17(18(22)26-29(19)12-13)20(30)25-15-11-23-5-4-16(15)28-8-6-27(7-9-28)14-2-1-3-14;1-26-5-6-27(10-13(26)11-30-2)15-3-4-22-8-14(15)24-19(29)16-17(21)25-28-9-12(20)7-23-18(16)28;1-25-2-4-26(5-3-25)12-6-13(19)21-8-11(12)23-17(28)14-15(20)24-27-9-10(18)7-22-16(14)27/h4,7,10-12H,5-6,8-9,13H2,1-3H3,(H2,23,27)(H,26,31);3-4,11-13H,5-10H2,1-2H3,(H2,22,26)(H,25,31);4-5,10-12,14H,1-3,6-9H2,(H2,22,26)(H,25,30);3-4,7-9,13H,5-6,10-11H2,1-2H3,(H2,21,25)(H,24,29);6-9H,2-5H2,1H3,(H2,19,21)(H2,20,24)(H,23,28)
InChIKeyFDVUYCPERFLJHS-UHFFFAOYSA-N
XLogP8.07
TPSA571.12 Ų
H-Bond Donors11
H-Bond Acceptors44
Rotatable Bonds24
Heavy Atoms151
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002162.57
LogP ≤ 58.07
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1044

Analyze 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

2-amino-6-chloro-N-[4-[4-(2-methoxyethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199225
2-amino-6-chloro-N-[4-[4-(3-methoxypyrrolidin-1-yl)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199339
2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199498
2-amino-6-chloro-N-[4-[4-(oxetan-3-yl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199546
2-amino-6-chloro-N-[4-[4-(6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199561
2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199765
2-amino-6-chloro-N-[4-[4-(3-methoxyazetidin-1-yl)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199782
2-amino-6-chloro-N-[4-[4-(3-methyloxetan-3-yl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90199816
2-amino-6-chloro-N-[4-(4-morpholin-4-ylpiperidin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90200162
2-amino-6-chloro-N-[4-(4-hydroxy-4-methylpiperidin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(1-oxo-1,4-thiazinan-4-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(trifluoromethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157524410
2-amino-6-chloro-N-(4-imidazol-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[4-(2-methylimidazol-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[4-[2-methyl-4-(trifluoromethyl)imidazol-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-(4-pyrazol-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[4-[4-(trifluoromethyl)imidazol-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157592250
2-amino-N-[4-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-(4-ethylpiperazin-1-yl)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[5-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[4-[4-(oxolan-3-yl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-[4-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158684303

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 158002061) is 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is CN(C)CCN1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN1CCN(c2cc(N)ncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COC1(CN(C)C)CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.COCC1CN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CCN1C.Nc1nn2cc(Cl)cnc2c1C(=O)Nc1cnccc1N1CCN(C2CCC2)CC1.
What is the InChIKey of 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is FDVUYCPERFLJHS-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H27ClN8O2.C20H26ClN9O.C20H23ClN8O.C19H23ClN8O2.C17H20ClN9O/c1-28(2)13-21(32-3)5-8-29(9-6-21)16-4-7-24-11-15(16)26-20(31)17-18(23)27-30-12-14(22)10-25-19(17)30;1-27(2)5-6-28-7-9-29(10-8-28)16-3-4-23-12-15(16)25-20(31)17-18(22)26-30-13-14(21)11-24-19(17)30;21-13-10-24-19-17(18(22)26-29(19)12-13)20(30)25-15-11-23-5-4-16(15)28-8-6-27(7-9-28)14-2-1-3-14;1-26-5-6-27(10-13(26)11-30-2)15-3-4-22-8-14(15)24-19(29)16-17(21)25-28-9-12(20)7-23-18(16)28;1-25-2-4-26(5-3-25)12-6-13(19)21-8-11(12)23-17(28)14-15(20)24-27-9-10(18)7-22-16(14)27/h4,7,10-12H,5-6,8-9,13H2,1-3H3,(H2,23,27)(H,26,31);3-4,11-13H,5-10H2,1-2H3,(H2,22,26)(H,25,31);4-5,10-12,14H,1-3,6-9H2,(H2,22,26)(H,25,30);3-4,7-9,13H,5-6,10-11H2,1-2H3,(H2,21,25)(H,24,29);6-9H,2-5H2,1H3,(H2,19,21)(H2,20,24)(H,23,28).
What are the key properties of 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2162.57 g/mol, XLogP of 8.07, 24 rotatable bonds, 11 hydrogen bond donors, and 44 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-[6-amino-4-(4-methylpiperazin-1-yl)-3-pyridinyl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-cyclobutylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-methoxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(methoxymethyl)-4-methylpiperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 158002061), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).