(2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide

C158H202F5N25O32 — CID 158062064

About (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide

(2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide (PubChem CID 158062064) has the molecular formula C158H202F5N25O32 and a molecular weight of 3058.49 g/mol. Its IUPAC name is (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide.

Molecular Properties

• Compound Name: (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide
• PubChem CID: 158062064
• Molecular Formula: C158H202F5N25O32
• Molecular Weight: 3058.49 g/mol
• Exact Mass: 3056.49
• IUPAC Name: (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide
• SMILES: CC(C)(NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1)C1CCN(c2ccc(F)cc2C#N)CC1.CCOc1c(F)cccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2)CC1.CCOc1ncccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2)cc1.C[C@@H]1CN(c2ccc(F)cc2C#N)CCC1CNC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1.N#Cc1cc(F)ccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCNCC2)CC1.N#Cc1cc(F)ccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCOCC2)CC1.O=C(NCc1ccc(-c2ccccc2Oc2ccccc2)cc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1
• InChI: InChI=1S/C27H28N2O5.C23H31FN4O4.C22H29FN4O4.C22H32FN3O5.C22H27N3O5.C21H28FN5O4.C21H27FN4O5/c30-24(25(31)27(33)29-16-6-7-17-29)26(32)28-18-19-12-14-20(15-13-19)22-10-4-5-11-23(22)34-21-8-2-1-3-9-21;1-23(2,26-21(31)19(29)20(30)22(32)28-9-3-4-10-28)16-7-11-27(12-8-16)18-6-5-17(24)13-15(18)14-25;1-14-13-27(18-5-4-17(23)10-16(18)11-24)9-6-15(14)12-25-21(30)19(28)20(29)22(31)26-7-2-3-8-26;1-2-31-20-16(23)6-5-7-17(20)25-12-8-15(9-13-25)14-24-21(29)18(27)19(28)22(30)26-10-3-4-11-26;1-2-30-21-17(6-5-11-23-21)16-9-7-15(8-10-16)14-24-20(28)18(26)19(27)22(29)25-12-3-4-13-25;22-16-1-2-17(15(11-16)12-23)26-7-3-14(4-8-26)13-25-20(30)18(28)19(29)21(31)27-9-5-24-6-10-27;22-16-1-2-17(15(11-16)12-23)25-5-3-14(4-6-25)13-24-20(29)18(27)19(28)21(30)26-7-9-31-10-8-26/h1-5,8-15,24-25,30-31H,6-7,16-18H2,(H,28,32);5-6,13,16,19-20,29-30H,3-4,7-12H2,1-2H3,(H,26,31);4-5,10,14-15,19-20,28-29H,2-3,6-9,12-13H2,1H3,(H,25,30);5-7,15,18-19,27-28H,2-4,8-14H2,1H3,(H,24,29);5-11,18-19,26-27H,2-4,12-14H2,1H3,(H,24,28);1-2,11,14,18-19,24,28-29H,3-10,13H2,(H,25,30);1-2,11,14,18-19,27-28H,3-10,13H2,(H,24,29)/t24-,25-;19-,20-;14-,15?,19-,20-;4*18-,19-/m1111111/s1
• InChIKey: FKTQMOYZDZTNJW-MQEHLKKRSA-N
• XLogP: 5.68
• TPSA: 802.29 Ų
• H-Bond Donors: 22
• H-Bond Acceptors: 43
• Rotatable Bonds: 48
• Heavy Atoms: 220
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3058.49
LogP ≤ 5	5.68
H-Bond Donors ≤ 5	22
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide?

The IUPAC name of (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide (CID 158062064) is (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide.

What is the SMILES notation for (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide?

The canonical SMILES for (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide is CC(C)(NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1)C1CCN(c2ccc(F)cc2C#N)CC1.CCOc1c(F)cccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2)CC1.CCOc1ncccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2)cc1.C[C@@H]1CN(c2ccc(F)cc2C#N)CCC1CNC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1.N#Cc1cc(F)ccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCNCC2)CC1.N#Cc1cc(F)ccc1N1CCC(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCOCC2)CC1.O=C(NCc1ccc(-c2ccccc2Oc2ccccc2)cc1)[C@H](O)[C@@H](O)C(=O)N1CCCC1.

What is the InChIKey of (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide?

The InChIKey is FKTQMOYZDZTNJW-MQEHLKKRSA-N. The full InChI is InChI=1S/C27H28N2O5.C23H31FN4O4.C22H29FN4O4.C22H32FN3O5.C22H27N3O5.C21H28FN5O4.C21H27FN4O5/c30-24(25(31)27(33)29-16-6-7-17-29)26(32)28-18-19-12-14-20(15-13-19)22-10-4-5-11-23(22)34-21-8-2-1-3-9-21;1-23(2,26-21(31)19(29)20(30)22(32)28-9-3-4-10-28)16-7-11-27(12-8-16)18-6-5-17(24)13-15(18)14-25;1-14-13-27(18-5-4-17(23)10-16(18)11-24)9-6-15(14)12-25-21(30)19(28)20(29)22(31)26-7-2-3-8-26;1-2-31-20-16(23)6-5-7-17(20)25-12-8-15(9-13-25)14-24-21(29)18(27)19(28)22(30)26-10-3-4-11-26;1-2-30-21-17(6-5-11-23-21)16-9-7-15(8-10-16)14-24-20(28)18(26)19(27)22(29)25-12-3-4-13-25;22-16-1-2-17(15(11-16)12-23)26-7-3-14(4-8-26)13-25-20(30)18(28)19(29)21(31)27-9-5-24-6-10-27;22-16-1-2-17(15(11-16)12-23)25-5-3-14(4-6-25)13-24-20(29)18(27)19(28)21(30)26-7-9-31-10-8-26/h1-5,8-15,24-25,30-31H,6-7,16-18H2,(H,28,32);5-6,13,16,19-20,29-30H,3-4,7-12H2,1-2H3,(H,26,31);4-5,10,14-15,19-20,28-29H,2-3,6-9,12-13H2,1H3,(H,25,30);5-7,15,18-19,27-28H,2-4,8-14H2,1H3,(H,24,29);5-11,18-19,26-27H,2-4,12-14H2,1H3,(H,24,28);1-2,11,14,18-19,24,28-29H,3-10,13H2,(H,25,30);1-2,11,14,18-19,27-28H,3-10,13H2,(H,24,29)/t24-,25-;19-,20-;14-,15?,19-,20-;4*18-,19-/m1111111/s1.

What are the key properties of (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide?

(2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide has a molecular weight of 3058.49 g/mol, XLogP of 5.68, 48 rotatable bonds, 22 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-N-[[(3S)-1-(2-cyano-4-fluorophenyl)-3-methylpiperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-morpholin-4-yl-4-oxobutanamide;(2R,3R)-N-[[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-piperazin-1-ylbutanamide;(2R,3R)-N-[2-[1-(2-cyano-4-fluorophenyl)piperidin-4-yl]propan-2-yl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[[4-(2-phenoxyphenyl)phenyl]methyl]-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[1-(2-ethoxy-3-fluorophenyl)piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-N-[[4-(2-ethoxy-3-pyridinyl)phenyl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide is sourced from PubChem (CID 158062064), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).