2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide

C191H160F8N30O26S8 — CID 158084466

IUPAC2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2cccs2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2cc(C(C)(F)F)cn2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccc(C)cc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccccc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2=NCC=C2C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C33H28FN5O5S.C32H27F3N6O4S.C32H26FN5O5S.C32H28FN5O4S.C31H26FN5O4S2.C31H25FN4O4S2/c1-18-10-12-39(29(40)14-18)33-30(32(41)35-2)22-15-21(26(17-28(22)44-33)37(3)45(4,42)43)24-9-8-19-11-13-38-25-7-5-6-23(34)20(25)16-27(38)31(19)36-24;1-32(34,35)18-15-37-41(16-18)31-28(30(42)36-2)21-12-20(25(14-27(21)45-31)39(3)46(4,43)44)23-9-8-17-10-11-40-24-7-5-6-22(33)19(24)13-26(40)29(17)38-23;1-34-31(40)29-21-15-20(25(36(2)44(3,41)42)17-27(21)43-32(29)38-13-5-4-9-28(38)39)23-11-10-18-12-14-37-24-8-6-7-22(33)19(24)16-26(37)30(18)35-23;1-17-10-12-35-29(17)31-28(32(39)34-2)21-14-20(25(16-27(21)42-31)37(3)43(4,40)41)23-9-8-18-11-13-38-24-7-5-6-22(33)19(24)15-26(38)30(18)36-23;1-16-34-15-27(42-16)30-28(31(38)33-2)20-12-19(24(14-26(20)41-30)36(3)43(4,39)40)22-9-8-17-10-11-37-23-7-5-6-21(32)18(23)13-25(37)29(17)35-22;1-33-31(37)28-20-14-19(24(35(2)42(3,38)39)16-26(20)40-30(28)27-8-5-13-41-27)22-10-9-17-11-12-36-23-7-4-6-21(32)18(23)15-25(36)29(17)34-22/h5-10,12,14-17H,11,13H2,1-4H3,(H,35,41);5-9,12-16H,10-11H2,1-4H3,(H,36,42);4-11,13,15-17H,12,14H2,1-3H3,(H,34,40);5-10,14-16H,11-13H2,1-4H3,(H,34,39);5-9,12-15H,10-11H2,1-4H3,(H,33,38);4-10,13-16H,11-12H2,1-3H3,(H,33,37)
InChIKeyFNINLEJJVVUULU-UHFFFAOYSA-N
MW3700.08 g/mol
LogP33.22
Rot. Bonds31

About 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide

2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide (PubChem CID 158084466) has the molecular formula C191H160F8N30O26S8 and a molecular weight of 3700.08 g/mol. Its IUPAC name is 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide.

Molecular Properties

Compound Name2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide
PubChem CID158084466
Molecular FormulaC191H160F8N30O26S8
Molecular Weight3700.08 g/mol
Exact Mass3696.98
IUPAC Name2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2cccs2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2cc(C(C)(F)F)cn2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccc(C)cc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccccc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2=NCC=C2C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C33H28FN5O5S.C32H27F3N6O4S.C32H26FN5O5S.C32H28FN5O4S.C31H26FN5O4S2.C31H25FN4O4S2/c1-18-10-12-39(29(40)14-18)33-30(32(41)35-2)22-15-21(26(17-28(22)44-33)37(3)45(4,42)43)24-9-8-19-11-13-38-25-7-5-6-23(34)20(25)16-27(38)31(19)36-24;1-32(34,35)18-15-37-41(16-18)31-28(30(42)36-2)21-12-20(25(14-27(21)45-31)39(3)46(4,43)44)23-9-8-17-10-11-40-24-7-5-6-22(33)19(24)13-26(40)29(17)38-23;1-34-31(40)29-21-15-20(25(36(2)44(3,41)42)17-27(21)43-32(29)38-13-5-4-9-28(38)39)23-11-10-18-12-14-37-24-8-6-7-22(33)19(24)16-26(37)30(18)35-23;1-17-10-12-35-29(17)31-28(32(39)34-2)21-14-20(25(16-27(21)42-31)37(3)43(4,40)41)23-9-8-18-11-13-38-24-7-5-6-22(33)19(24)15-26(38)30(18)36-23;1-16-34-15-27(42-16)30-28(31(38)33-2)20-12-19(24(14-26(20)41-30)36(3)43(4,39)40)22-9-8-17-10-11-37-23-7-5-6-21(32)18(23)13-25(37)29(17)35-22;1-33-31(37)28-20-14-19(24(35(2)42(3,38)39)16-26(20)40-30(28)27-8-5-13-41-27)22-10-9-17-11-12-36-23-7-4-6-21(32)18(23)15-25(36)29(17)34-22/h5-10,12,14-17H,11,13H2,1-4H3,(H,35,41);5-9,12-16H,10-11H2,1-4H3,(H,36,42);4-11,13,15-17H,12,14H2,1-3H3,(H,34,40);5-10,14-16H,11-13H2,1-4H3,(H,34,39);5-9,12-15H,10-11H2,1-4H3,(H,33,38);4-10,13-16H,11-12H2,1-3H3,(H,33,37)
InChIKeyFNINLEJJVVUULU-UHFFFAOYSA-N
XLogP33.22
TPSA671.71 Ų
H-Bond Donors6
H-Bond Acceptors46
Rotatable Bonds31
Heavy Atoms263
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003700.08
LogP ≤ 533.22
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1046

Analyze 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide with MolForge

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Related Compounds

5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-(N-methylmethylsulfonamido)-2-(2-methylthiazol-5-yl)benzofuran-3-carboxamide
CID 77845760
2-(2-ethyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 77845762
6-(ethylsulfonylamino)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide
CID 118573575
2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 118583347
2-[1-[2-[15-fluoro-4-[2-(2-methoxy-3-pyridinyl)-3-(methylcarbamoyl)-6-[methyl(methylsulfonyl)amino]-1-benzofuran-5-yl]-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-13-yl]ethyl]pyrazol-4-yl]-5-(15-fluoro-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 123206821
2-[1-[[4-[2-(6-ethoxy-3-pyridinyl)-3-(methylcarbamoyl)-6-[methyl(methylsulfonyl)amino]-1-benzofuran-5-yl]-15-fluoro-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-13-yl]methyl]pyrazol-4-yl]-5-(15-fluoro-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 123279607
2-[2-[2-[2-(2-ethyl-1,3-thiazol-5-yl)-3-(methylcarbamoyl)-6-[methyl(methylsulfonyl)amino]-1-benzofuran-5-yl]-11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-9-yl]-1,3-thiazol-5-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 123461461
5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-[2-[2-[11-fluoro-2-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-6-[methyl(methylsulfonyl)amino]-1-benzofuran-5-yl]-6-methyl-5,6-dihydroindolo[2,1-a][2,6]naphthyridin-9-yl]ethyl]-1,3-thiazol-5-yl]-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 123737042
2-[2-[2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-3-(methylcarbamoyl)-6-[methyl(methylsulfonyl)amino]-1-benzofuran-5-yl]-11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-9-yl]-1H-pyrazol-2-ium-5-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
CID 123801238
5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-(6-fluoro-3-pyridinyl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-[6-(trifluoromethyl)-3-pyridinyl]-1-benzofuran-3-carboxamide
CID 144681447
5-(15-fluoro-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(15-fluoro-8-oxa-3,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-[6-(trifluoromethyl)-3-pyridinyl]-1-benzofuran-3-carboxamide
CID 144681678
CID 157151283
CID 157151283

Frequently Asked Questions

What is the IUPAC name of 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide?
The IUPAC name of 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide (CID 158084466) is 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide.
What is the SMILES notation for 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide?
The canonical SMILES for 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide is CNC(=O)c1c(-c2cccs2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2cc(C(C)(F)F)cn2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccc(C)cc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-n2ccccc2=O)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2=NCC=C2C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.
What is the InChIKey of 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide?
The InChIKey is FNINLEJJVVUULU-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H28FN5O5S.C32H27F3N6O4S.C32H26FN5O5S.C32H28FN5O4S.C31H26FN5O4S2.C31H25FN4O4S2/c1-18-10-12-39(29(40)14-18)33-30(32(41)35-2)22-15-21(26(17-28(22)44-33)37(3)45(4,42)43)24-9-8-19-11-13-38-25-7-5-6-23(34)20(25)16-27(38)31(19)36-24;1-32(34,35)18-15-37-41(16-18)31-28(30(42)36-2)21-12-20(25(14-27(21)45-31)39(3)46(4,43)44)23-9-8-17-10-11-40-24-7-5-6-22(33)19(24)13-26(40)29(17)38-23;1-34-31(40)29-21-15-20(25(36(2)44(3,41)42)17-27(21)43-32(29)38-13-5-4-9-28(38)39)23-11-10-18-12-14-37-24-8-6-7-22(33)19(24)16-26(37)30(18)35-23;1-17-10-12-35-29(17)31-28(32(39)34-2)21-14-20(25(16-27(21)42-31)37(3)43(4,40)41)23-9-8-18-11-13-38-24-7-5-6-22(33)19(24)15-26(38)30(18)36-23;1-16-34-15-27(42-16)30-28(31(38)33-2)20-12-19(24(14-26(20)41-30)36(3)43(4,39)40)22-9-8-17-10-11-37-23-7-5-6-21(32)18(23)13-25(37)29(17)35-22;1-33-31(37)28-20-14-19(24(35(2)42(3,38)39)16-26(20)40-30(28)27-8-5-13-41-27)22-10-9-17-11-12-36-23-7-4-6-21(32)18(23)15-25(36)29(17)34-22/h5-10,12,14-17H,11,13H2,1-4H3,(H,35,41);5-9,12-16H,10-11H2,1-4H3,(H,36,42);4-11,13,15-17H,12,14H2,1-3H3,(H,34,40);5-10,14-16H,11-13H2,1-4H3,(H,34,39);5-9,12-15H,10-11H2,1-4H3,(H,33,38);4-10,13-16H,11-12H2,1-3H3,(H,33,37).
What are the key properties of 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide?
2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide has a molecular weight of 3700.08 g/mol, XLogP of 33.22, 31 rotatable bonds, 6 hydrogen bond donors, and 46 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4-methyl-2H-pyrrol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-methyl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-oxo-1-pyridinyl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-thiophen-2-yl-1-benzofuran-3-carboxamide is sourced from PubChem (CID 158084466), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).